2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product Name: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.: 1195-66-0
Chemical Name: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Synonyms: METHOXYBORONIC ACID PINACOL ESTER;MeO-Bpin;Crizotinib Impurity 15;Methyl pinacolyl borate;2-Methoxy-4,4,5,5-tetramethyL;Methoxyboroniceacidpinacolester;Methoxyboronic acid pinacol este;Mehtoxy boronic acid pinacol ester;2-Methoxy-4,4,5,5-tetramethyl-1,3,2;METHYL DIHYDROGEN BORATE PINACOL ESTER
CBNumber: CB7135431
Molecular Formula: C7H15BO3
Formula Weight: 158
MOL File: 1195-66-0.mol

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2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Property

Boiling point:: 120°C 228mm
Density: 0.9642 g/mL at 25 °C
refractive index: 1.4096
Flash point:: 108°F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: clear liquid
color: Colorless to Almost colorless
Sensitive: Moisture Sensitive
BRN: 2827758
InChI: InChI=1S/C7H15BO3/c1-6(2)7(3,4)11-8(9-5)10-6/h1-5H3
InChIKey: JZZJAWSMSXCSIB-UHFFFAOYSA-N
SMILES: O1C(C)(C)C(C)(C)OB1OC
CAS DataBase Reference: 1195-66-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 10-36
Safety Statements: 26
RIDADR: 1993
WGK Germany: 3
HazardClass: 3
PackingGroup: III
HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 673943
Product name: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity: 96%
Packaging: 5g
Price: $47.84
Updated: 2025/07/31

Sigma-Aldrich

Product number: 673943
Product name: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity: 96%
Packaging: 25g
Price: $117.76
Updated: 2025/07/31

TCI Chemical

Product number: M1714
Product name: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $31
Updated: 2025/07/31

TCI Chemical

Product number: M1714
Product name: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $104
Updated: 2025/07/31

TRC

Product number: M292913
Product name: Methoxyboronicacidpinacolester
Packaging: 5g
Price: $55
Updated: 2021/12/16

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2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Chemical Properties,Usage,Production

Uses

suzuki reaction

Uses

It is employed in the synthesis, optical, and electrochemical properties of novel copolymers on the basis of benzothiadiazole and electron-rich arene units.

Synthesis

124-38-9

25015-63-8

10221-56-4

1195-66-0

The general procedure for the synthesis of 2,2'-oxybis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) and 2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane from carbon dioxide and pinacolborane was as follows: a solution of (PhPSiP)Ni(η3-C8H13) (1.0 mg, 0.0014 mmol) and 1 ,3,5-trimethoxybenzene (11.5 mg, 0.068 mmol) were added to a J.YY NMR tube and the solution was frozen. After cooling, a layer of pinacolborane (9.9 μL, 0.068 mmol) was added. On a double Schlenk line, the headspace was evacuated and passed through 1 atm of CO2 at room temperature.After 15 min, almost complete depletion of pinacolborane was observed, along with the appearance of three major products. The products were identified by comparison with those reported by Sabo-Etienne.After 15 min, products a, b, and c were present in a 61:5:34 ratio with unreacted pinacolborane. However, the product c was gradually consumed over time, and after 12 h, all pinacolborane was consumed, leaving only traces of product c in the reaction mixture.The product integrals showed the presence of 13% 2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborole pentacyclic, 85% 2,2'-oxybis(4,4,5,5-tetramethyl-1,3,2-dioxaborole heterocyclopentane) and a small amount of unidentified by-products. In addition, a peak corresponding to formaldehyde at 8.72 ppm was observed.

References

[1] Polyhedron, 2014, vol. 84, p. 37 - 43
[2] Journal of the American Chemical Society, 2010, vol. 132, # 26, p. 8872 - 8873
[3] Angewandte Chemie - International Edition, 2012, vol. 51, # 45, p. 11343 - 11345
[4] Angew. Chem., 2012, vol. 05, # 741, p. 11505 - 11507
[5] Journal of the American Chemical Society, 2015, vol. 137, # 16, p. 5332 - 5335

2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Suppliers

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View Lastest Price from 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1195-66-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1195-66-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1195-66-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

1195-66-0, 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneRelated Search:

Pentaborane 2-CYCLOHEXYLOXY-4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLANE 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Crizotinib Impurity 15

METHOXYBORONIC ACID PINACOL ESTER

Mehtoxy boronic acid pinacol ester

Methyl pinacolyl borate

2-METHOXY-4,4,5,5-TETRAMETHYL-1,3,2-DIO&

Methoxyboroniceacidpinacolester

2-Methoxyboronic acid, pinacol cyclic ester

Methoxyboronic acid pinacol este

2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, Methyl pinacolyl borate

3-hydroxy-2,3-diMethylbutan-2-yl Methyl hydrogen borate

MeO-Bpin

2-Methoxy-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(Methoxyboronic acid pinacol ester)

2-Methoxy-4,4,5,5-tetramethyl-1,3,2

2-METHOXY-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

Boric acid, cyclic tetramethylethylene methyl ester

2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane&gt

2-Methoxy-4,4,5,5-tetramethyL

METHYL DIHYDROGEN BORATE PINACOL ESTER

1,3,2-Dioxaborolane, 2-methoxy-4,4,5,5-tetramethyl-

1195-66-0

C7H15BO3

Organoborates

Organometallic Reagents

Boric Acid Esters

Boric Acid Triesters

B (Classes of Boron Compounds)

Boronic Acids and Derivatives

B (Classes of Boron Compounds)

Boric Acid Esters

Boric Acid Triesters