SCH 32615
- Product Name
- SCH 32615
- CAS No.
- 83861-02-3
- Chemical Name
- SCH 32615
- Synonyms
- SCH 32615;N-[N-[(S)-1-Carboxy-2-phenylethyl]-L-phenylalanyl]-β-alanine
- CBNumber
- CB71355096
- Molecular Formula
- C21H24N2O5
- Formula Weight
- 384.42566
- MOL File
- 83861-02-3.mol
SCH 32615 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: 125 mg/mL (325.16 mM)
- form
- Solid
- color
- Off-white to yellow
SCH 32615 Chemical Properties,Usage,Production
Uses
SCH 32615 is an enkephalinase (the enzymes responsible for the degradation of endogenous enkephalins) inhibitor. SCH 32615 can enhance surgery- and pregnancy-induced analgesia in mice[1][2].
in vivo
SCH 32615 (150 mg/kg; s.c.) enhances surgery activated endogenous analgesia in mice[1].
References
[1] Jayaram A, et, al. An enkephalinase inhibitor, SCH 32615, augments analgesia induced by surgery in mice. Anesthesiology. 1995 May;82(5):1283-7. DOI:10.1097/00000542-199505000-00024
[2] Jayaram A, et, al. SCH 32615, an enkephalinase inhibitor, enhances pregnancy-induced analgesia in mice. Anesth Analg. 1995 May;80(5):944-8. DOI:10.1097/00000539-199505000-00015
[3] Chipkin RE, et, al. Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic. J Pharmacol Exp Ther. 1988 Jun;245(3):829-38. PMID:3164388
SCH 32615 Preparation Products And Raw materials
Raw materials
Preparation Products
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