fibrostatin C

Product Name: fibrostatin C
CAS No.: 91776-47-5
Chemical Name: fibrostatin C
Synonyms: P-23924C;fibrostatin C;N-Acetyl-S-[(5,8-dihydro-1-hydroxy-3,6-dimethoxy-5,8-dioxonaphthalen-2-yl)methyl]-L-cysteine
CBNumber: CB71371605
Molecular Formula: C18H19NO8S
Formula Weight: 409.413
MOL File: 91776-47-5.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0025526
Product name: FIBROSTATIN C
Purity: 95.00%
Packaging: 5MG
Price: $496.46
Updated: 2021/12/16

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fibrostatin C Chemical Properties,Usage,Production

Description

Fibrostatin C is a prolyl 4-hydroxylase (PH) inhibitor produced by Streptomyces catenulae subsp. griseospora.

Uses

Fibrostatin C (P-23924C) is an orally active prolyl hydroxylase inhibitor that also inhibits collagen biosynthesis. Fibrostatin C also increases the number of cytoplasmic granules immunoreactive with antibodies to collagen I or III. Fibrostatin C inhibits the secretion of type I collagen in Tenon's capsule fibroblasts. Fibrostatin C is promising for research of the wound fibrotic response in the wound of glaucoma filtering surgery[1][2].

References

[1] Ishimaru T, et al. Inhibition of prolyl hydroxylase activity and collagen biosynthesis by fibrostatin C, a novel inhibitor produced by Streptomyces catenulae subsp. griseospora No. 23924. J Antibiot (Tokyo). 1988 Nov;41(11):1668-74. DOI:10.7164/antibiotics.41.1668
[2] Saika S, et al. Effect of fibrostatin C, an inhibitor of prolyl 4-hydroxylase, on collagen secretion by human Tenon's capsule fibroblasts in vitro. Graefes Arch Clin Exp Ophthalmol. 1996 Aug;234 Suppl 1:S214-22. DOI:10.1007/BF02343075

fibrostatin C Preparation Products And Raw materials

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fibrostatin C Suppliers

China 3 United States 2 Global 5

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TargetMol Chemicals Inc.

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91776-47-5, fibrostatin CRelated Search:

2-METHOXY-1,4-NAPHTHOQUINONE 2-Hydroxy-1,4-naphoquinone N-ACETYL-S-BENZYL-DL-CYSTEINE 4-METHYL-2-[(METHYLTHIO)METHYL]PHENOL 2-hydroxyjuglone 1,4-DIHYDRO-2,7-DIMETHOXYNAPHTHALENE 2,5-DIMETHYL-P-ANISALDEHYDE N-ACETYL-S-BENZYL-L-CYSTEINE S-P-METHYLBENZYL-L-CYSTEINE H-CYS(CH3BZL)-OL fibrostatin C

fibrostatin C

N-Acetyl-S-[(5,8-dihydro-1-hydroxy-3,6-dimethoxy-5,8-dioxonaphthalen-2-yl)methyl]-L-cysteine

P-23924C

91776-47-5