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ETHYLENESULFATE

Product Name
ETHYLENESULFATE
CAS No.
1072-53-3
Chemical Name
ETHYLENESULFATE
Synonyms
DTD;1,3,2-DIOXATHIOLANE 2,2-DIOXIDE;NSC 526594;glycolsulfate;Vinyl sulfate;GLYCOLSULPHATE;ETHYLENESULFATE;ETHYLENESULPHATE;Ethylenesulfate ,98%;1,2-ETHYLENE SULFATE
CBNumber
CB7138159
Molecular Formula
C2H4O4S
Formula Weight
124.12
MOL File
1072-53-3.mol
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ETHYLENESULFATE Property

Melting point:
95-97 °C (lit.)
Boiling point:
231.1±7.0℃ (760 Torr)
Density 
1.604±0.06 g/cm3 (20 ºC 760 Torr)
vapor pressure 
0.91-1.7Pa at 20-25℃
refractive index 
1.5090 (estimate)
Flash point:
93.5±18.2℃
storage temp. 
2-8°C
solubility 
Chloroform, Methanol
form 
solid
color 
White to Off-White
InChI
InChI=1S/C2H4O4S/c3-7(4)5-1-2-6-7/h1-2H2
InChIKey
ZPFAVCIQZKRBGF-UHFFFAOYSA-N
SMILES
C1OS(=O)(=O)OC1
LogP
-0.45 at 23℃ and pH1.4-1.7
Surface tension
66.8mN/m at 1g/L and 20℃
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Safety

Risk Statements 
22
WGK Germany 
3
RTECS 
JH4800000
HS Code 
29209085
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H351Suspected of causing cancer

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
471690
Product name
1,3,2-Dioxathiolane 2,2-dioxide
Purity
98%
Packaging
5g
Price
$136
Updated
2025/07/31
TCI Chemical
Product number
D2830
Product name
1,3,2-Dioxathiolane 2,2-Dioxide
Purity
>98.0%(GC)
Packaging
5g
Price
$44
Updated
2025/07/31
TCI Chemical
Product number
D2830
Product name
1,3,2-Dioxathiolane 2,2-Dioxide
Purity
>98.0%(GC)
Packaging
25g
Price
$129
Updated
2025/07/31
TRC
Product number
D486865
Product name
1,3,2-Dioxathiolane 2,2-Dioxide
Packaging
100g
Price
$835
Updated
2021/12/16
AK Scientific
Product number
Z6926
Product name
Ethylenesulfate
Packaging
1g
Price
$14
Updated
2021/12/16
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ETHYLENESULFATE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

1,3,2-Dioxathiolane 2,2-Dioxide is an alkylating agent with carcinogenic activty.

Uses

1,3,2-Dioxathiolane 2,2-dioxide may be employed in the preparation of imidazolidinium salts.

Synthesis

Cyclic sulfates of 1,2-diols (1,3,2-dioxathiolane 2,2-dioxides) are most easily prepared in a two-step procedure (eq 1). The reaction of a 1,2-diol with Thionyl Chloride leads to a cyclic sulfite, which is then oxidized to the corresponding cyclic sulfate (1). Direct conversion of a 1,2-diol to a cyclic sulfate using Sulfuryl Chloride is generally less efficient.

Toxics Screening Level

The initial threshold screening level (ITSL) for 1,3,2-dioxathiolane,2,2-dioxide (CAS #1072-53-3) is 0.1 μg/m3 annual averaging time.

Precautions

The structural similarity between cyclic sulfates and Dimethyl Sulfate must be recognized. Dimethyl sulfate, and to a lesser extent, ethylene sulfate, are carcinogenic and potent alkylating agents that are toxic by inhalation and ingestion. Cyclic sulfates must, as a result, be treated with extreme care.

References

[1] Patent: CN108822073, 2018, A. Location in patent: Paragraph 0017-0028
[2] Patent: CN106187989, 2016, A. Location in patent: Paragraph 0016
[3] Acta Chemica Scandinavica, 1996, vol. 50, # 2, p. 170 - 177
[4] Journal of the Chemical Society, Chemical Communications, 1983, # 23, p. 1392 - 1394
[5] Molecules, 2005, vol. 10, # 9, p. 1169 - 1178

ETHYLENESULFATE Preparation Products And Raw materials

Raw materials

Xylene Silver sulfate 1,2-Dibromoethane

Preparation Products

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ETHYLENESULFATE Suppliers

Americas 1 Canada 1 China 355 Europe 1 India 2 Japan 1 Switzerland 1 United Kingdom 3 United States 24 Global 389
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from ETHYLENESULFATE manufacturers

Ningxia Jinhua Chemical Co.,Ltd
Product
Ethylene sulfate(DTD) 1072-53-3
Price
US $0.00/KG
Min. Order
100KG
Purity
99.6%
Supply Ability
10mt
Release date
2021-02-09
Yancheng Green Chemicals Co.,Ltd
Product
Ethylene sulfate(DTD) 1072-53-3
Price
US $0.00/KG
Min. Order
100KG
Purity
99.6%
Supply Ability
10mt
Release date
2021-02-09
Changde Changlian Chemical Co., Ltd.
Product
Ethylene sulfate(DTD) 1072-53-3
Price
US $0.00/KG
Min. Order
100KG
Purity
99.6%
Supply Ability
10mt
Release date
2021-02-09

1072-53-3, ETHYLENESULFATERelated Search:

Lincomycin 1,2,2,2-ETHANETETROL CYCLIC DISULFATE (+)-DIMETHYL 2,3-O-SULFONYL-D-TARTRATE METHYL-2,3-O-SULFURYL-5-O-PIVALOYL-BETA-D-RIBOFURANOSIDE AURORA KA-604 ETHYLENESULFATE PROPANE 1,2-CYCLIC SULFATE DIMETHYL L-TARTRATE CYCLIC SULFATE 1,4-DICHLOROBUTANE-2S-3S-DIOL SULFATE 3-METHOXYMETHYL-16ALPHA,17BETA-EPIESTRIOL-O-CYCLIC SULFONE

  • ethyleneglycol,cyclicsulfate
  • 1,3,2-Dioxathiolan-2,2-oxide (DTD)
  • 1,3,2-Dioxathiolane 2,2-dioxide 98%
  • Ethylenesulfate≥ 99% (GC)
  • glycolsulfate
  • 1,3,2-Dioxathiolane,2,2-dioxides
  • 1,2-ETHYLENE SULFATE
  • 1,3,2-DIOXATHIOLANE 2,2-DIOXIDE
  • Ethylenesulfate ,98%
  • NSC 526594
  • sulfuricacid,cyclicethyleneester
  • DTD
  • ETHYLENESULFATE
  • ETHYLENESULPHATE
  • GLYCOLSULPHATE
  • 1,3,2-DIOXATHIOLANE2,2-DIOXIDE/ETHYLENESULFATE
  • 2,2-dioxido-1,3,2-dioxathiolane
  • Ethylene sulfate 1072-53-3
  • 1,3,2-Dioxathiolane 2,2-dioxide 1072-53-3
  • 1,2-Ethylene Sulfate DTD 1072-53-3
  • 1,3,2-Dioxathiolane2,2-Dioxide&gt
  • 1,3,2-Dioxathiolane 2,2-Dioxide,>98%
  • Vinyl sulfate
  • 1,3,2-Dioxathiolan-2,2-oxide
  • ETHYLENESULFATE ISO 9001：2015 REACH
  • 3,2-Dioxathiolane 2,2-dioxide, 97%+
  • 1,3,2-Dioxathiolane, 2,2-dioxide (9CI, ACI)
  • DTD 1,3,2-Dioxathiolane 2,2-dioxide
  • 1,3,2-Dioxathiolan-2,2-dioxide
  • 1,3 2-Dioxathiolane-2, 2-dioxide1,3 2-Dioxathiolane-2, 2-dioxide
  • 1,3,2-Oxathiazole2,2-dioxide
  • Ethylenedithiocarbonate
  • EthyleneSulfateasanAdditiveforLithium-IonBatteryElectrolyte
  • 1,3,2-DIOXATHIOLANE 2,2-DIOXID 99.5%
  • 1072-53-3
  • C2H4O4S
  • Heterocyclic Building Blocks
  • Others
  • S-Containing
  • Building Blocks
  • Fine Chemical
  • Used in organic synthesis of sterically hydroxyethyl synthetic drug intermediates
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Biphenyl & Diphenyl ether
  • Heterocyclic Compounds
  • Heterocyclic Building Blocks
  • Others
  • S-Containing
  • 3
  • 1072-53-3