Raxofelast

Product Name: Raxofelast
CAS No.: 128232-14-4
Chemical Name: Raxofelast
Synonyms: IRFI-016;Raxofelast;2-Benzofuranacetic acid, 5-(acetyloxy)-2,3-dihydro-4,6,7-trimethyl-;2-(5-acetoxy-4,6,7-trimethyl-2,3-dihydrobenzofuran-2-yl)acetic acid
CBNumber: CB71385424
Molecular Formula: C15H18O5
Formula Weight: 278.302
MOL File: 128232-14-4.mol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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Raxofelast Chemical Properties,Usage,Production

Uses

Raxofelast (IRFI-016) is an antioxidant agent in various models of ischemia-reperfusion injury. Raxofelast has antiproliferative activity in H2O2-stimulated rat aortic smooth muscle cells. Raxofelast attenuates the activation of mitogen-activating protein kinase (MAPK), ERK kinase 1, 2 (MEK1,2) and protein kinase C (PKC) without affecting Ras expression[1].

References

[1] Kyung-Hye Lee, et al. Antiproliferative mechanisms of raxofelast (IRFI-016) in H2O2-stimulated rat aortic smooth muscle cells. Eur J Pharmacol. 2004, 484, 2-3. DOI:10.1016/j.ejphar.2003.11.012

Raxofelast Preparation Products And Raw materials

Raw materials

Preparation Products

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Raxofelast Suppliers

China 7 United States 2 Global 9

TargetMol Chemicals Inc.

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Shanghai Yifei Biotechnology Co. , Ltd.

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TargetMol Chemicals Inc.

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Sangon Biotech (Shanghai) Co.,Ltd.

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Shanghai Amole Biotechnology Co., Ltd.

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Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39040
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128232-14-4, RaxofelastRelated Search:

Trimethylhydroquinone 3-(4-METHOXYPHENOXY)PROPANOIC ACID 4-HYDROXY-2,3,6-TRIMETHYLPHENYL ACETATE Raxofelast 2,3-DIHYDRO-1-BENZOFURANACETIC ACID 3-(2,5-DIMETHYL-PHENOXY)-PROPIONIC ACID 3-M-TOLYLOXY-PROPIONIC ACID 2,3-DIHYDRO-BENZOFURAN-5-OL

Raxofelast

IRFI-016

2-(5-acetoxy-4,6,7-trimethyl-2,3-dihydrobenzofuran-2-yl)acetic acid

2-Benzofuranacetic acid, 5-(acetyloxy)-2,3-dihydro-4,6,7-trimethyl-

128232-14-4