ChemicalBook > CAS DataBase List > galgravin

galgravin

Product Name: galgravin
CAS No.: 528-63-2
Chemical Name: galgravin
Synonyms: galgravin;(±)-Galgravin;galgravin USP/EP/BP;Galgravin, 10 mM in DMSO;inhibit,Inhibitor,Apoptosis,Galgravin;(2S,3S,4R,5R)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane;rel-(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran;Furan, 2,5-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-, (2R,3R,4S,5S)-rel-
CBNumber: CB71393726
Molecular Formula: C22H28O5
Formula Weight: 372.45
MOL File: 528-63-2.mol

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galgravin Property

Melting point:: 139-140 °C(Solv: methanol (67-56-1))
Boiling point:: 479.1±45.0 °C(Predicted)
Density: 1.082±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: soluble; DMSO: soluble
form: A solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 300291
Product name: Galgravin
Packaging: 10mg
Price: $575
Updated: 2021/12/16

Arctom

Product number: SY232804
Product name: (±)-Galgravin
Packaging: 10mg
Price: $638.18
Updated: 2021/12/16

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galgravin Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Heather vine.

Uses

Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2].

Definition

ChEBI: Galgravin is a member of the class of aryltetrahydrofurans carrying two 3,4-dimethoxyphenyl substituents at positions 2 and 5 as well as two methyl groups at positions 3 and 4. It has a role as a bone density conservation agent, a neuroprotective agent, a platelet aggregation inhibitor and a plant metabolite. It is an aryltetrahydrofuran, a dimethoxybenzene, a ring assembly and a lignan.

References

[1] da Silva Filho AA, et al. Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and rats. J Pharm Pharmacol. 2004 Sep;56(9):1179-84. DOI:10.1211/0022357044058
[2] Ponci V, et al. Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells. Molecules. 2015 Jul 15;20(7):12757-68. DOI:10.3390/molecules200712757

galgravin Preparation Products And Raw materials

Raw materials

Preparation Products

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528-63-2, galgravinRelated Search:

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galgravin

Furan, 2,5-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-, (2R,3R,4S,5S)-rel-

galgravin USP/EP/BP

(2S,3S,4R,5R)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane

inhibit,Inhibitor,Apoptosis,Galgravin

rel-(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran

Galgravin, 10 mM in DMSO

(±)-Galgravin

528-63-2