ChemicalBook > CAS DataBase List > 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine

7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine

Product Name
7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine
CAS No.
83255-86-1
Chemical Name
7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine
Synonyms
9-tetraen-5-amine;9-tetrazabicyclo[4.3.0]nona-2;4-Amino-3-Bromo-pyrazolo[3,4-d]pyrimidine;3-BROMO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE;3-bromo-2H-pyrazolo[4,3-e]pyrimidin-4-amine;3-bromo-2H-pyrazolo[3,4-d]pyrimidin-4-amine;4-amine, 3-bromo-1H-Pyrazolo[3,4-d]pyrimidin;4-Amino-3-bromo-1H-pyrazolo[3,4-d]pyrimidine;4-Amino-3-bromo-1H-pyrazole(3,4-d)pyrimidine;3-Bromo-1H-pyrazolo[3,4-d]pyrimidinyl-4-amine
CBNumber
CB71459422
Molecular Formula
C5H4BrN5
Formula Weight
214.02
MOL File
83255-86-1.mol
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7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine Property

Melting point:
350°C(lit.)
Boiling point:
287.4±50.0 °C(Predicted)
Density 
2.54±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder to crystal
pka
10.32±0.20(Predicted)
color 
White to Light yellow
InChI
InChI=1S/C5H4BrN5/c6-3-2-4(7)8-1-9-5(2)11-10-3/h1H,(H3,7,8,9,10,11)
InChIKey
GZQVGSRUUTUJNG-UHFFFAOYSA-N
SMILES
C1=NC(N)=C2C(Br)=NNC2=N1
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE001441
Product name
3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity
Aldrich
Packaging
1g
Price
$497
Updated
2025/07/31
TCI Chemical
Product number
B4630
Product name
3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity
>97.0%(HPLC)(N)
Packaging
1g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
B4630
Product name
3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity
>97.0%(HPLC)(N)
Packaging
5g
Price
$164
Updated
2024/03/01
TRC
Product number
B997215
Product name
3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Packaging
100mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-W008671
Product name
3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity
99.45%
Packaging
5g
Price
$19
Updated
2021/12/16
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7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine Chemical Properties,Usage,Production

Chemical Properties

Yellow solid

Synthesis

2380-63-4

83255-86-1

The general procedure for the synthesis of 3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine using 4-aminopyrazolo[3,4-d]pyrimidine as starting material was as follows: 1H-pyrazolo[3,4-d]pyrimidin-4-amine (20.0 g, 148.0 mmol) and N-bromosuccinimide (27.7 g, 155.4 mmol) were suspended in N,N- dimethylformamide (DMF, 400 mL). The reaction mixture was heated to 80 °C and the reaction was stirred at this temperature for 2.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature, followed by slow dropwise addition of water (800 mL) to quench the reaction. The resulting precipitate was collected by filtration and suspended in saturated sodium sulfite solution (100 mL). The solid product was filtered again and washed sequentially with water (3 x 100 mL) and cold ethanol (2 x 50 mL). Finally, the product was dried under vacuum to afford 3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine as a beige solid (22.7 g, 105.9 mmol, 72% yield).

References

[1] Patent: WO2017/17619, 2017, A1. Location in patent: Page/Page column 8-9
[2] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 17, p. 4774 - 4786
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982, vol. 18, # 7, p. 753 - 755
[4] Khimiya Geterotsiklicheskikh Soedinenii, 1982, # 7, p. 982 - 984
[5] Patent: EP2548877, 2013, A1. Location in patent: Paragraph 0416

7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine manufacturers

Shaanxi Xianhe Biotech Co., Ltd
Product
3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine 83255-86-1
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000kg
Release date
2025-04-17
Nanjing Fred Technology Co., Ltd
Product
3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine 83255-86-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-28
Henan Fengda Chemical Co., Ltd
Product
7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine 83255-86-1
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09

83255-86-1, 7-bromo-2,4,8,9-tetrazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amineRelated Search:


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  • 83255-86-1