Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
- Product Name
- Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
- CAS No.
- 179087-93-5
- Chemical Name
- Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
- Synonyms
- SB 271258;4-(2,4-Dioxothiazolidin-5-ylmethyl)phenoxyacetic acid;2-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid;2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]acetic acid;Acetic acid, [4-[(2,4-dioxo-5-thiazolidinyl)Methyl]phenoxy]-;Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
- CBNumber
- CB71465780
- Molecular Formula
- C12H11NO5S
- Formula Weight
- 281.28
- MOL File
- 179087-93-5.mol
Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
N-Bromosuccinimide Price
- Product number
- P000236155
- Product name
- 2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
- Purity
- 97+%
- Packaging
- 250mg
- Price
- $161
- Updated
- 2021/12/16
- Product number
- P000236155
- Product name
- 2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
- Purity
- 97+%
- Packaging
- 1g
- Price
- $403
- Updated
- 2021/12/16
- Product number
- P000236155
- Product name
- 2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
- Purity
- 97+%
- Packaging
- 100mg
- Price
- $101
- Updated
- 2021/12/16
- Product number
- P000236155
- Product name
- 2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
- Purity
- 97+%
- Packaging
- 5g
- Price
- $1209
- Updated
- 2021/12/16
- Product number
- A110661
- Product name
- 2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)aceticacid
- Purity
- 97%
- Packaging
- 100mg
- Price
- $146
- Updated
- 2021/12/16
Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Chemical Properties,Usage,Production
Synthesis
172648-06-5
179087-93-5
The general procedure for the synthesis of 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid from the compound (CAS:172648-06-5) is as follows: 1. a methanol (0.65 L) solution of [4-[[2,4-dioxo-1,3-thiazolidin-5-yl]methyl]phenoxy]ethyl acetate (110 g, 0.36 mol) was mixed with a water (0.65 L) solution of Na2CO3 (200 g, 1.88 mol) at 0 °C and the reaction was stirred for 5 hours. 2. After completion of the reaction, methanol was removed by distillation under reduced pressure at 25~30 °C. 3. Water was added to the residue and acidified with hydrochloric acid. 4. The precipitated solid was filtered to afford the target product 4-(2,4-dioxothiazolin-5-ylmethyl)phenoxyacetic acid (80 g, 80% yield). Product characterization: melting point 181-183 °C. 1H NMR (DMSO-d6) δ: 12.40 (bs, 1H, D2O exchangeable), 8.60 (bs, 1H, D2O exchangeable), 7.16 (d, J = 8.40 Hz, 2H), 6.50 (d, J = 8.40 Hz, 2H), 4.87 (dd, J = 9.14,4.20 Hz, 1H), 4.65 (s, 2H), 3.32 (dd, J = 14.12,4.20 Hz, 1H), 3.05 (dd, J = 14.12,9.14 Hz, 1H).
References
[1] Patent: US6310069, 2001, B1
Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Preparation Products And Raw materials
Raw materials
Preparation Products
Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Suppliers
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