ChemicalBook > CAS DataBase List > Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-

Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-

Product Name
Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
CAS No.
179087-93-5
Chemical Name
Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
Synonyms
SB 271258;4-(2,4-Dioxothiazolidin-5-ylmethyl)phenoxyacetic acid;2-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid;2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]acetic acid;Acetic acid, [4-[(2,4-dioxo-5-thiazolidinyl)Methyl]phenoxy]-;Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
CBNumber
CB71465780
Molecular Formula
C12H11NO5S
Formula Weight
281.28
MOL File
179087-93-5.mol
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Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Ark Pharm
Product number
P000236155
Product name
2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
Purity
97+%
Packaging
250mg
Price
$161
Updated
2021/12/16
Ark Pharm
Product number
P000236155
Product name
2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
Purity
97+%
Packaging
1g
Price
$403
Updated
2021/12/16
Ark Pharm
Product number
P000236155
Product name
2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
Purity
97+%
Packaging
100mg
Price
$101
Updated
2021/12/16
Ark Pharm
Product number
P000236155
Product name
2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
Purity
97+%
Packaging
5g
Price
$1209
Updated
2021/12/16
Ambeed
Product number
A110661
Product name
2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)aceticacid
Purity
97%
Packaging
100mg
Price
$146
Updated
2021/12/16
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Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Chemical Properties,Usage,Production

Synthesis

172648-06-5

179087-93-5

The general procedure for the synthesis of 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid from the compound (CAS:172648-06-5) is as follows: 1. a methanol (0.65 L) solution of [4-[[2,4-dioxo-1,3-thiazolidin-5-yl]methyl]phenoxy]ethyl acetate (110 g, 0.36 mol) was mixed with a water (0.65 L) solution of Na2CO3 (200 g, 1.88 mol) at 0 °C and the reaction was stirred for 5 hours. 2. After completion of the reaction, methanol was removed by distillation under reduced pressure at 25~30 °C. 3. Water was added to the residue and acidified with hydrochloric acid. 4. The precipitated solid was filtered to afford the target product 4-(2,4-dioxothiazolin-5-ylmethyl)phenoxyacetic acid (80 g, 80% yield). Product characterization: melting point 181-183 °C. 1H NMR (DMSO-d6) δ: 12.40 (bs, 1H, D2O exchangeable), 8.60 (bs, 1H, D2O exchangeable), 7.16 (d, J = 8.40 Hz, 2H), 6.50 (d, J = 8.40 Hz, 2H), 4.87 (dd, J = 9.14,4.20 Hz, 1H), 4.65 (s, 2H), 3.32 (dd, J = 14.12,4.20 Hz, 1H), 3.05 (dd, J = 14.12,9.14 Hz, 1H).

References

[1] Patent: US6310069, 2001, B1

Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

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Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]- Suppliers

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179087-93-5, Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-Related Search:


  • Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]-
  • SB 271258
  • 2-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
  • Acetic acid, [4-[(2,4-dioxo-5-thiazolidinyl)Methyl]phenoxy]-
  • 2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]acetic acid
  • 4-(2,4-Dioxothiazolidin-5-ylmethyl)phenoxyacetic acid
  • 179087-93-5
  • Drug Intermediates