Diosbulbin C

Product Name: Diosbulbin C
CAS No.: 20086-07-1
Chemical Name: Diosbulbin C
Synonyms: Diosbulbin C;Airpotato yam C;4H-3a,6-Methanofuro[2,3-d][2]benzoxepin-7-carboxylic acid, 2-(3-furanyl)decahydro-9-hydroxy-10b-methyl-4-oxo-, (2R,3aS,6S,6aS,7R,9R,10aR,10bS)-;(2R)-2-(3-Furyl)-1,2,6,6aβ,7,8,9,10,10aα,10b-decahydro-9α-hydroxy-10bβ-methyl-4-oxo-4H-3aβ,6β-methanofuro[2,3-d][2]benzoxepine-7α-carboxylic acid
CBNumber: CB71470218
Molecular Formula: C19H22O7
Formula Weight: 362.37
MOL File: 20086-07-1.mol

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Diosbulbin C Property

Melting point:: 247-250 °C
Boiling point:: 606.0±55.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 4.36±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD32002074
Product name: DiosbulbinC
Purity: 95+%
Packaging: 5mg
Price: $922
Updated: 2021/12/16

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Diosbulbin C Chemical Properties,Usage,Production

Uses

Diosbulbin C is a diterpene lactone component, which can be extracted from traditional Chinese medicine Dioscorea bulbifera L.. Diosbulbin C possesses high anticancer activity in non-small cell lung cancer (NSCLC). Diosbulbin C could induce cell cycle arrest at G0/G1 phase in NSCLC. Diosbulbin C also inhibits the proliferation of NSCLC cells, possibly by downregulating the expression/activation of AKT, DHFR, and TYMS[1][1].

Definition

ChEBI: Diosbulbin C is a naphthofuran.

References

[1] Zhu Z, et al. Diosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest. BMC Complement Med Ther. 2023 Dec 4;23(1):436. DOI:10.1186/s12906-023-04245-9

Diosbulbin C Preparation Products And Raw materials

Raw materials

Preparation Products

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Diosbulbin C Suppliers

China 35 United States 3 Global 38

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20086-07-1, Diosbulbin CRelated Search:

Diosbulbin C

(2R)-2-(3-Furyl)-1,2,6,6aβ,7,8,9,10,10aα,10b-decahydro-9α-hydroxy-10bβ-methyl-4-oxo-4H-3aβ,6β-methanofuro[2,3-d][2]benzoxepine-7α-carboxylic acid

Airpotato yam C

4H-3a,6-Methanofuro[2,3-d][2]benzoxepin-7-carboxylic acid, 2-(3-furanyl)decahydro-9-hydroxy-10b-methyl-4-oxo-, (2R,3aS,6S,6aS,7R,9R,10aR,10bS)-

20086-07-1