4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE

Product Name: 4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE
CAS No.: 2110-25-0
Chemical Name: 4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE
Synonyms: UCCF029;UCCF-029;UCCF 029;UC(CF)029;UC(CF)-029;UC(CF) 029;4H-Naphtho[1,2-b]pyran-4-one, 2-(4-pyridinyl)-;4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE
CBNumber: CB71477848
Molecular Formula: C18H11NO2
Formula Weight: 273.29
MOL File: 2110-25-0.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 016744
Product name: 2-Pyridin-4-yl-benzo[h]chromen-4-one
Packaging: 1g
Price: $545
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0090423
Product name: 2-PYRIDIN-4-YL-BENZO[H]CHROMEN-4-ONE
Purity: 95.00%
Packaging: 500MG
Price: $775.01
Updated: 2021/12/16

AK Scientific

Product number: 7179AD
Product name: 2-Pyridin-4-yl-benzo[h]chromen-4-one
Packaging: 1g
Price: $785
Updated: 2021/12/16

Crysdot

Product number: CD11166748
Product name: 2-(Pyridin-4-yl)-4H-benzo[h]chromen-4-one
Purity: 97%
Packaging: 5g
Price: $874
Updated: 2021/12/16

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4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE Chemical Properties,Usage,Production

Description

UCCF-029 is a novel cystic fibrosis transmembrane conductance regulator (CFTR) activator.

Uses

UCCF-029 Free base is a potent activator of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. UCCF-029 Free base exhibits enhanced activity through benzannulation of the flavone A-ring at the 7,8-position. UCCF-029 Free base serves as a structural guide for the development of more effective flavonoid analogues. UCCF-029 Free base demonstrates improved potency compared to apigenin in activating wild-type CFTR. UCCF-029 Free base also exhibits potential for activating the mutant CFTR (G551D-CFTR) though not as robustly as apigenin.

Definition

ChEBI: 2-pyridin-4-yl-4-benzo[h][1]benzopyranone is an organic heterotricyclic compound and an organooxygen compound.

References

[1] Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain

4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE Preparation Products And Raw materials

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4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE Suppliers

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2110-25-0, 4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATERelated Search:

2-pyridin-4-ylchromen-4-one 4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE

4-(4-OXO-4H-BENZO[H]CHROMEN-2-YL)-PYRIDINIUM BISULFATE

4H-Naphtho[1,2-b]pyran-4-one, 2-(4-pyridinyl)-

UC(CF) 029

UC(CF)029

UC(CF)-029

UCCF 029

UCCF029

UCCF-029

2110-25-0