3-Bromo-5-nitrobenzene-1,2-diamine
- Product Name
- 3-Bromo-5-nitrobenzene-1,2-diamine
- CAS No.
- 69399-60-6
- Chemical Name
- 3-Bromo-5-nitrobenzene-1,2-diamine
- Synonyms
- Guaiacol Impurity 19-d5;3-Bromo-5-nitro-1,2-diaminobenzene;3-BROMO-5-NITROBENZENE-1,2-DIAMINE;1,2-Benzenediamine, 3-bromo-5-nitro-
- CBNumber
- CB71478360
- Molecular Formula
- C6H6BrN3O2
- Formula Weight
- 232.03
- MOL File
- 69399-60-6.mol
3-Bromo-5-nitrobenzene-1,2-diamine Property
- Melting point:
- 203-205 °C
- Boiling point:
- 426.5±40.0 °C(Predicted)
- Density
- 1.901±0.06 g/cm3(Predicted)
- pka
- 0.81±0.10(Predicted)
3-Bromo-5-nitrobenzene-1,2-diamine Chemical Properties,Usage,Production
Synthesis
Sodium sulfide nonahydrate (96 g, 400 mmol) and sulfur (12.8 g, 400 mmol) in a mixture of water and ethanol was heated at reflux under nitrogen for 1 h. The solution was added to a stirred suspension of 2-bromo-4,6-dinitrobenzenamine (104.8 g, 400 mmol) and ammonium chloride (20.8 g, 400 mmol) in a solution of 400 mL of water and 700 mL of ethanol. The mixture was stirred at 65° C for 30 min. Then 400 mL of 2N NaOH solution was added dropwise during 30 min and the mixture was then stirred for 15 minutes at 65° C. After cooling, the mixture was poured onto a mixture of 2N HCl (400 mL), 1 kg ice and 1 L of water, stirred for 15 min to complete the reaction and extracted with ethyl acetate (1 L*3). The combined organic layers were dried over sodium sulphate and evaporated to give the crude product (3-Bromo-5-nitrobenzene-1,2-diamine) (90 g, 97%) as a rust-colored solid, which was used for the next step without further purification.
3-Bromo-5-nitrobenzene-1,2-diamine Preparation Products And Raw materials
Raw materials
Preparation Products
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