1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE

Product Name: 1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE
CAS No.: 143426-52-2
Chemical Name: 1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE
Synonyms: CPD2800-A3;1-[4-(ChloroMethyl)phenyl]pyrazole;1H-Pyrazole,1-[4-(chloroMethyl)phenyl]-;1-[4-(Chloromethyl)phenyl]-1H-pyrazole 95%;1-[4-(chloromethyl)phenyl]-1H-pyrazole(SALTDATA: FREE)
CBNumber: CB71490623
Molecular Formula: C10H9ClN2
Formula Weight: 192.64
MOL File: 143426-52-2.mol

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1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE Property

Boiling point:: 303.9±25.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 0.05±0.10(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C10H9ClN2/c11-8-9-2-4-10(5-3-9)13-7-1-6-12-13/h1-7H,8H2
InChIKey: PAINSRDHMRYAGK-UHFFFAOYSA-N
SMILES: N1(C2=CC=C(CCl)C=C2)C=CC=N1

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Safety

WGK Germany: 3
HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CBR00371
Product name: 1-[4-(Chloromethyl)phenyl]-1H-pyrazole
Purity: Aldrich
Packaging: 1g
Price: $128
Updated: 2025/07/31

TRC

Product number: C587945
Product name: 1-[4-(Chloromethyl)phenyl]-1H-pyrazole
Packaging: 500mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC135977
Product name: 1-[4-(Chloromethyl)phenyl]-1H-pyrazole
Packaging: 500mg
Price: $115
Updated: 2021/12/16

ChemScene

Product number: CS-0046907
Product name: 1-(4-(Chloromethyl)phenyl)-1H-pyrazole
Packaging: 1g
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC135977
Product name: 1-[4-(Chloromethyl)phenyl]-1H-pyrazole
Packaging: 250mg
Price: $75
Updated: 2021/12/16

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1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

143426-49-7

143426-52-2

General procedure for the synthesis of 1-(4-(chloromethyl)phenyl)-1H-pyrazole from 4-pyrazol-1-ylbenzenemethanol: To a solution of [4-(1H-pyrazol-1-yl)phenyl]methanol (24.0 g) in 1,2-dichloroethane (200 mL) was added slowly and dropwise to thionyl chloride (26.3 g) in an ice bath under cooling. After the dropwise addition, the reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the reaction mixture was concentrated by distillation under reduced pressure and the resulting residue was washed with tert-butyl methyl ether to give the final target product 1-(4-(chloromethyl)phenyl)-1H-pyrazole (23.5 g). The product was characterized by 1HNMR (400 MHz, CDC13): δ 4.62 (2H, s), 6.48 (1H, t, J = 2.0 Hz), 7.47 (2H, d, J = 8.8 Hz), 7.69 (2H, d, J = 8.8 Hz), 7.73 (1H, d, J = 2.0 Hz), 7.93 (1H, d, J = 2.4 Hz ).

References

[1] European Journal of Medicinal Chemistry, 1992, vol. 27, # 3, p. 219 - 228
[2] Patent: WO2015/163485, 2015, A1. Location in patent: Paragraph 0388

1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE Suppliers

China 76 India 2 Ukraine 1 United Kingdom 2 United States 8 Global 89

Alchem Pharmtech,Inc.

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View Lastest Price from 1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 1-[4-(ChloroMethyl)phenyl]pyrazole 143426-52-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-09-29

Career Henan Chemical Co

Product: 1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE 143426-52-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-14

143426-52-2, 1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDERelated Search:

1-[4-(CHLOROMETHYL)PHENYL]-3,5-DIMETHYL-1H-PYRAZOLE HYDROCHLORIDE 4-(1H-PYRAZOL-1-YL)BENZOYL CHLORIDE 4-[3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZOYL CHLORIDE 1-[4-(CHLOROMETHYL)PHENYL]-3,5-DIMETHYL-1H-PYRAZOLE 1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE 1-[4-(CHLOROMETHYL)PHENYL]-1H-PYRAZOLE HYDROCHLORIDE

1-[4-(chloromethyl)phenyl]-1H-pyrazole(SALTDATA: FREE)

1-[4-(ChloroMethyl)phenyl]pyrazole

1H-Pyrazole,1-[4-(chloroMethyl)phenyl]-

1-[4-(Chloromethyl)phenyl]-1H-pyrazole 95%

CPD2800-A3

143426-52-2