indolin-6-ol
- Product Name
- indolin-6-ol
- CAS No.
- 4770-37-0
- Chemical Name
- indolin-6-ol
- Synonyms
- indolin-6-OH;indolin-6-ol;6-Hydroxyindoline;2,3-dihydro-1H-indol-6-ol;1h-indol-6-ol,2,3-dihydro-;6-Hydroxyindoline indolin-6-ol in stock Factory
- CBNumber
- CB71515865
- Molecular Formula
- C8H9NO
- Formula Weight
- 135.16
- MOL File
- 4770-37-0.mol
indolin-6-ol Property
- Boiling point:
- 302.4±31.0 °C(Predicted)
- Density
- 1.196±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 10.44±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CHM0094366
- Product name
- 1H-INDOL-6-OL,2,3-DIHYDRO-
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.96
- Updated
- 2021/12/16
- Product number
- A159886
- Product name
- Indolin-6-ol
- Purity
- 95%
- Packaging
- 5g
- Price
- $632
- Updated
- 2021/12/16
- Product number
- SC-26284
- Product name
- indolin-6-ol
- Purity
- 95
- Packaging
- 1g
- Price
- $1150
- Updated
- 2021/12/16
- Product number
- SC-26284
- Product name
- indolin-6-ol
- Purity
- 95
- Packaging
- 5g
- Price
- $1350
- Updated
- 2021/12/16
- Product number
- CM125397
- Product name
- indolin-6-ol
- Purity
- 95%
- Packaging
- 5g
- Price
- $1384
- Updated
- 2021/12/16
indolin-6-ol Chemical Properties,Usage,Production
Synthesis
2380-86-1
4770-37-0
General procedure for the synthesis of 6-hydroxyindoline from 6-hydroxyindole: Sodium cyanoborohydride (NaBH3CN, 1.4 g, 22.60 mmol) was slowly added to a solution of 6-hydroxyindole (1.0 g, 7.51 mmol) in acetic acid (AcOH, 20 mL) at 0 °C. Subsequently, the reaction mixture was stirred under nitrogen (N2) protection for 3 h at room temperature. Upon completion of the reaction, the reaction was quenched with saturated ammonium chloride (NH4Cl, 3 mL) solution and concentrated under reduced pressure to give a residue. The residue was redissolved in ethyl acetate (EtOAc, 50 mL) and washed sequentially with saturated sodium bicarbonate (NaHCO3, 50 mL) solution and brine (50 mL). The organic phase was dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated. The residue was purified by fast column chromatography using petroleum ether/ethyl acetate (5:1→3:1→2:1, v/v) as eluent to afford the target product 6-hydroxyindoline (0.61 g, 60% yield) as a brown solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) and 13C NMR (101 MHz, DMSO-d6).
References
[1] ChemMedChem, 2016, vol. 11, # 23, p. 2607 - 2620
[2] European Journal of Medicinal Chemistry, 2018, vol. 157, p. 380 - 396
indolin-6-ol Preparation Products And Raw materials
Raw materials
Preparation Products
indolin-6-ol Suppliers
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- +86-25-68710855, +86-25-68710897
- Fax
- 025-68710856
- sales@springpharma.net
- Country
- China
- ProdList
- 1261
- Advantage
- 62
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 42446
- Advantage
- 60
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- Country
- China
- ProdList
- 2930
- Advantage
- 58
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5674
- Advantage
- 50
- Tel
- 13770809694
- Fax
- +86 25 56203983
- googlexu_0114@sina.com
- Country
- China
- ProdList
- 990
- Advantage
- 58
- Tel
- 400-027-6116 18086000087
- Fax
- QQ: 2680733325
- sales@chemgreatwall.com
- Country
- China
- ProdList
- 1559
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 10110
- Advantage
- 58
View Lastest Price from indolin-6-ol manufacturers
- Product
- 6-Hydroxyindoline indolin-6-ol in stock Factory 4770-37-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- TOP 3 Factory in China
- Supply Ability
- Top 3 production capacity Factory
- Release date
- 2019-04-03