derquantel

Product Name: derquantel
CAS No.: 187865-22-1
Chemical Name: derquantel
Synonyms: derquantel;Unii-0L0ugk6oox;2-Deoxoparaherquamide;Derquantel in methanol;2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
CBNumber: CB71518503
Molecular Formula: C28H37N3O4
Formula Weight: 479.61
MOL File: 187865-22-1.mol

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derquantel Property

Boiling point:: 641.3±55.0 °C(Predicted)
Density: 1.34
storage temp.: Store at -20°C
solubility: DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form: A solid
pka: 15.18±0.60(Predicted)
color: White to off-white
JECFA Number: 75

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19441
Product name: Derquantel
Purity: ≥98%
Packaging: 5mg
Price: $321
Updated: 2024/03/01

Cayman Chemical

Product number: 19441
Product name: Derquantel
Purity: ≥98%
Packaging: 25mg
Price: $1280
Updated: 2024/03/01

ApexBio Technology

Product number: C4619
Product name: Derquantel
Packaging: 25mg
Price: $1381
Updated: 2021/12/16

ApexBio Technology

Product number: C4619
Product name: Derquantel
Packaging: 5mg
Price: $345
Updated: 2021/12/16

AK Scientific

Product number: 2982DC
Product name: Derquantel
Packaging: 5mg
Price: $436
Updated: 2021/12/16

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derquantel Chemical Properties,Usage,Production

Description

Derquantel is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes. A combination of derquantel and the macrocyclic lactone, abamectin , has been found to have synergistic anthelmintic effects against gastrointestinal nematode parasites in sheep.

Uses

Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel isa potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin. Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.

Definition

ChEBI: Derquantel is an azaspiro compound.

derquantel Preparation Products And Raw materials

Raw materials

Preparation Products

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derquantel Suppliers

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187865-22-1, derquantelRelated Search:

derquantel

2-Deoxoparaherquamide

Unii-0L0ugk6oox

2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962

Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-

Derquantel in methanol

187865-22-1

C28H37N3O4