3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxylic acid Property

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

Red to Dark Red

Stability:

Light Sensitive

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxylic acid Chemical Properties,Usage,Production

Description

Pyrrothiogatain is a novel inhibitor of GATA family proteins, targeting the DNA-binding activity of GATA3 and other members of the GATA family, inhibiting the interaction between GATA3 and SOX4, significantly suppressing Th2 cell differentiation, without impairing Th1 cell differentiation, and inhibiting the expression and production of Th2 cytokines.

Uses

3-(2,5-Dimethyl-1H-pyrrol-1-yl)-2-thiophenecarboxylic Acid is involved in the regulation of GATA3 DNA binding activity in Th2 cells.