Z-D-ALA-NH2

Product Name: Z-D-ALA-NH2
CAS No.: 151378-81-3
Chemical Name: Z-D-ALA-NH2
Synonyms: Z-D-ALA-NH2;CBZ-D-Ala-NH2;Z-D-ALANINE-NH2;CBZ-D-ALANINAMIDE;Z-D-ALANINE AMIDE;N-Cbz-D-alanine amide;(R)-2-(Cbz-amino)propanamide;Z-D-alanine amide≥ 98% (HPLC);N-Benzyloxycarbonyl-D-alaninamide;N-ALPHA-CARBOBENZOXY-D-ALANINE AMIDE
CBNumber: CB7155851
Molecular Formula: C11H14N2O3
Formula Weight: 222.24
MOL File: 151378-81-3.mol

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Z-D-ALA-NH2 Property

Melting point:: 132-134 °C
Boiling point:: 443.8±38.0 °C(Predicted)
Density: 1.199±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 11.17±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A614010
Product name: Z-D-Ala-NH2
Packaging: 250mg
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 260725
Product name: Z-D-alanine amide
Packaging: 1g
Price: $333
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA48887
Product name: Z-D-alanine amide
Packaging: 5G
Price: $251.1
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA48887
Product name: Z-D-alanine amide
Packaging: 2g
Price: $97.1
Updated: 2021/12/16

AK Scientific

Product number: 7872AH
Product name: Z-D-Ala-NH2
Packaging: 25g
Price: $107
Updated: 2021/12/16

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Z-D-ALA-NH2 Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Synthesis

26607-51-2

151378-81-3

General procedure for the synthesis of benzyl (R)-(1-amino-1-oxo-2-propyl)carbamate from (R)-2-((benzyloxy)carbonyl)amino)propionic acid: to a colorless solution of 150 mg (0.50 mmol) of (R)-2-((benzyloxy)carbonyl)amino)propionic acid in 10 mL of tetrahydrofuran (THF) was added at 0 °C 67 μL ( 0.70 mmol, 1.4 eq.) ethyl chloroformate and 209 μL (1.5 mmol, 3.0 eq.) triethylamine. After stirring for 30 min at 0 °C, 0.75 mL of 1.0 M aqueous ammonium chloride (0.75 mmol, 1.5 equiv) was added to the colorless suspension at 0 °C. The mixture was continued to be stirred at 0 °C for 30 min, after which 5 mL of water was added to the reaction mixture. The colorless clear solution was extracted with 30 mL of ethyl acetate and the aqueous layer was extracted with another 20 mL of ethyl acetate. The organic layers were combined, washed with 5 mL of saturated brine and dried with anhydrous magnesium sulfate. The crude product was purified by silica gel column chromatography using ethyl acetate as eluent to give 129 mg (86% yield) of the target product (R)-(1-amino-1-oxo-2-propyl)carbamic acid benzyl ester.

References

[1] Tetrahedron Asymmetry, 2017, vol. 28, # 12, p. 1690 - 1699
[2] Bioorganic and Medicinal Chemistry Letters, 1996, vol. 6, # 6, p. 631 - 636
[3] Journal of Medicinal Chemistry, 2000, vol. 43, # 10, p. 1910 - 1926
[4] Chemistry Letters, 2013, vol. 42, # 6, p. 580 - 582

Z-D-ALA-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-D-ALA-NH2 Suppliers

China 44 India 1 Japan 1 United Kingdom 1 United States 6 Global 53

Shanghai Hanhong Scientific Co.,Ltd.

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Shanghai GL Peptide Ltd.

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Aikon International Limited

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Shanghai Jizhi Biochemical Technology Co. Ltd.

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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

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Shanghai Jifeng Biotechnology Co., Ltd.

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Fax: 021-61263399
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151378-81-3, Z-D-ALA-NH2Related Search:

Z-D-ALA-OSU N-BENZYLOXYCARBONYL-D-ALANINOL N-alpha-Benzyloxycarbonyl-D-alanine p-nitrophenyl ester N-Cbz-D-Alanine Z-D-ALA-GLY-OH Z-D-PRO-NH2 Z-D-PHE-VAL-OH Z-D-VAL-LYS(Z)-OH Z-D-ALA-NH2 Z-D-LEU-D-ALA-OH Z-D-ALA-D-ALA-OME Z-D-VAL-LEU-OH Z-D-ALA-PHE-OH Z-D-PHE-NH2 Z-D-LEU-GLY-OH N-CBZ-D-PHE-PHE-GLY Z-D-GLU-TYR-OH Z-D-ALA-D-ALA-OH

CBZ-D-ALANINAMIDE

N-ALPHA-CARBOBENZOXY-D-ALANINE AMIDE

Z-D-ALANINE AMIDE

Z-D-ALA-NH2

Z-D-ALANINE-NH2

N-[(1R)-2-Amino-1-methyl-2-oxoethyl]carbamic acid phenylmethyl ester

N-Benzyloxycarbonyl-D-alaninamide

N-Cbz-D-alanine amide

Z-D-alanine amide≥ 98% (HPLC)

benzyl N-[(1R)-1-carbamoylethyl]carbamate

Carbamic acid, N-[(1R)-2-amino-1-methyl-2-oxoethyl]-, phenylmethyl ester

benzyl N-[(2R)-1-amino-1-oxopropan-2-yl]carbamate

CBZ-D-Ala-NH2

(R)-2-(Cbz-amino)propanamide

151378-81-3