3-bromo-2-(bromomethyl)pyridine
- Product Name
- 3-bromo-2-(bromomethyl)pyridine
- CAS No.
- 754131-60-7
- Chemical Name
- 3-bromo-2-(bromomethyl)pyridine
- Synonyms
- Morpholine,4-(5-bromopropyl)-;3-bromo-2-(bromomethyl)pyridine;Pyridine, 3-bromo-2-(bromomethyl)-;4-bromo-2,5-dimethoxybenzene-2-sulfonylchloride
- CBNumber
- CB71558747
- Molecular Formula
- C6H5Br2N
- Formula Weight
- 250.92
- MOL File
- 754131-60-7.mol
3-bromo-2-(bromomethyl)pyridine Property
- Boiling point:
- 250.9±25.0 °C(Predicted)
- Density
- 1.955±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- 1.08±0.22(Predicted)
- Appearance
- Pink to red Solid
- InChI
- InChI=1S/C6H5Br2N/c7-4-6-5(8)2-1-3-9-6/h1-3H,4H2
- InChIKey
- FVIZOBDAEIFYGH-UHFFFAOYSA-N
- SMILES
- C1(CBr)=NC=CC=C1Br
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- FB161272
- Product name
- 3-Bromo-2-(bromomethyl)pyridine
- Packaging
- 500mg
- Price
- $325
- Updated
- 2021/12/16
- Product number
- FB161272
- Product name
- 3-Bromo-2-(bromomethyl)pyridine
- Packaging
- 1g
- Price
- $500
- Updated
- 2021/12/16
- Product number
- HCH0046434
- Product name
- 3-BROMO-2-(BROMOMETHYL)PYRIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.89
- Updated
- 2021/12/16
- Product number
- 5579CZ
- Product name
- 3-Bromo-2-(bromomethyl)pyridine
- Packaging
- 2g
- Price
- $590
- Updated
- 2021/12/16
- Product number
- FB161272
- Product name
- 3-Bromo-2-(bromomethyl)pyridine
- Packaging
- 2g
- Price
- $700
- Updated
- 2021/12/16
3-bromo-2-(bromomethyl)pyridine Chemical Properties,Usage,Production
Synthesis
38749-79-0
754131-60-7
General procedure for the synthesis of 3-bromo-2-(bromomethyl)pyridine from 2-methyl-3-bromopyridine: a mixture of 2-methyl-3-bromopyridine (1 g, 5.8 mmol), benzoyl peroxide (101 mg, 0.4 mmol) and N-bromosuccinimide (NBS, 1.1 g, 6.39 mmol) in carbon tetrachloride (CCI4, 58 mL) was was heated under reflux conditions for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature, the reaction was quenched with water (H2O) and extracted with dichloromethane (DCM, 3 x 30 mL). The organic layers were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (CC), and 3-bromo-2-(bromomethyl)pyridine (1.1 g, 78% yield) was obtained as a yellow oil using a solvent mixture of petroleum ether (PE) and ethyl acetate (EA) (15:1) as eluent.
References
[1] Patent: WO2011/107248, 2011, A1. Location in patent: Page/Page column 43
[2] Patent: EP2784077, 2014, A1. Location in patent: Paragraph 0060; 0061
[3] Patent: US2014/343089, 2014, A1. Location in patent: Paragraph 0066
[4] Patent: WO2009/51715, 2009, A1. Location in patent: Page/Page column 33
[5] Patent: WO2004/98607, 2004, A1. Location in patent: Page/Page column 51
3-bromo-2-(bromomethyl)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-bromo-2-(bromomethyl)pyridine Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 3-bromo-2-(bromomethyl)pyridine manufacturers
- Product
- 3-bromo-2-(bromomethyl)pyridine 754131-60-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-22
- Product
- 3-bromo-2-(bromomethyl)pyridine 754131-60-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-14