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tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate

Product Name
tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
CAS No.
230301-11-8
Chemical Name
tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
Synonyms
tert-butyl 1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate;tert-butyl 6;7-dihydro-1H-pyrazolo[4;3-c]pyridine-5(4H)-carboxylate;5-Boc-4,5,6,7-Tetrahydropyrazolo[4,3-c];5-Boc-4,5,6,7-Tetrahydropyrazolo[4,3-c]pyridine;t-Butyl 1H,4H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxylate;5-t-Butoxycarbonyl-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine;tert-butyl 1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxylate;tert-Butyl 6,7-dihydro-1H-pyrazolo4,3-cpyridin-5(4H)--carboxylate
CBNumber
CB71562405
Molecular Formula
C11H17N3O2
Formula Weight
223.27
MOL File
230301-11-8.mol
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tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate Property

Boiling point:
388.0±42.0 °C(Predicted)
Density 
1.200±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
14.81±0.20(Predicted)
Appearance
Off-white to yellow Solid
InChI
InChI=1S/C11H17N3O2/c1-11(2,3)16-10(15)14-5-4-9-8(7-14)6-12-13-9/h6H,4-5,7H2,1-3H3,(H,12,13)
InChIKey
BHYPERDTLBCHAE-UHFFFAOYSA-N
SMILES
C1N(C(OC(C)(C)C)=O)CCC2NN=CC1=2
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-D1539
Product name
tert-Butyl1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
Packaging
5g
Price
$127
Updated
2021/12/16
ChemScene
Product number
CS-D1539
Product name
tert-Butyl1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
Packaging
1g
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB51599
Product name
5-Boc-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine
Packaging
500mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB51599
Product name
5-Boc-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine
Packaging
1g
Price
$193.2
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB51599
Product name
5-Boc-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine
Packaging
2g
Price
$309.1
Updated
2021/12/16
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tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate Chemical Properties,Usage,Production

Synthesis

1310796-19-0

230301-11-8

General procedure for the synthesis of tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate from the compound (CAS: 1310796-19-0): to tert-butyl (Z)-3-((dimethylamino)methylene)-4-oxo-piperidine-1-carboxylate (8.8 g, 34.6 mmol) in ethanol (EtOH, 50 mL) hydrazine hydrate (N2H4-H2O, 200 mL) was slowly added to the solution at 0°C. The reaction mixture was stirred at 20°C for 12 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The resulting residue was isolated and purified by column chromatography to afford the target product tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (7 g, 95% yield). The product was analyzed by LCMS and showed m/z: 224.2 [M + H]+.

References

[1] Patent: WO2015/200677, 2015, A2. Location in patent: Paragraph 00806; 00807

tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate Suppliers

China 146 China Hong Kong 1 France 1 Germany 4 India 2 United Kingdom 3 United States 31 Global 188
Shanghai Carlow Chemicals Co., Ltd.
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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021-54306202 13764082696
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View Lastest Price from tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate manufacturers

Career Henan Chemical Co
Product
tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate 230301-11-8
Price
US $0.01/KG
Min. Order
1KG
Purity
98%； 99%
Supply Ability
1kg; 5kg; 10kg；25kg
Release date
2020-01-07

230301-11-8, tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylateRelated Search:

tert-butyl 6,7-dihydro-3-iodopyrazolo[1,5-a]pyrazine-5(4H)-carboxylate 5-(TERT-BUTOXYCARBONYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE-2-CARBOXYLIC ACID 5-Boc-1-Phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine TERT-BUTYL HEXAHYDROPYRROLO[3,4-B]PYRROLE-5(1H)-CARBOXYLATE tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate 2-METHYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER 2H-PYRAZOLO[4,3-C]PYRIDINE-2-ACETIC ACID, 5-[(1,1-DIMETHYLETHOXY)CARBONYL]-4,5,6,7-TETRAHYDRO-, ETHYL ESTER TERT-BUTYL 3-(4-METHOXYPHENYL)-6,7-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE-5(4H)-CARBOXYLATE TERT-BUTYL 2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLATE 2-(6-METHYL-3-PYRIDAZINYL)-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER TERT-BUTYL 3-(TRIFLUOROMETHYL)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLATE TERT-BUTYL 3-(4-FLUOROPHENYL)-6,7-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE-5(4H)-CARBOXYLATE 2-CYCLOPENTYL-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID, TERT-BUTYL ESTER TERT-BUTYL 3-PHENYL-6,7-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE-5(4H)-CARBOXYLATE TERT-BUTYL 2-(6-CHLOROPYRIDAZIN-3-YL)-2,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLATE TERT-BUTYL 3-(4-CHLOROPHENYL)-6,7-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE-5(4H)-CARBOXYLATE 2-(2-METHYL-PYRIDIN-4-YL)-2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLIC ACID TERT-BUTYL ESTER TERT-BUTYL 1-METHYL-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDINE-5-CARBOXYLATE

  • tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
  • 1,4,6,7-Tetrahydro-1H-pyrazolo[4,3-C]pyridine-5-carboxylic acid tert-butyl ester
  • 5-Boc-4,5,6,7-Tetrahydropyrazolo[4,3-c]pyridine
  • 3-c]pyridine-5(4H)-carboxylate
  • 7-dihydro-1H-pyrazolo[4
  • tert-butyl 6
  • tert-butyl 1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
  • TERT-BUTYL 6,7-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE-5(4H)-CARBOXYLATE(WX619173)
  • 1,4,6,7-Tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester
  • tert-butyl 1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxylate
  • t-Butyl 1H,4H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxylate
  • 5-t-Butoxycarbonyl-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine
  • 5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester
  • 5-Boc-4,5,6,7-Tetrahydropyrazolo[4,3-c]
  • tert-Butyl 6,7-dihydro-1H-pyrazolo4,3-cpyridin-5(4H)--carboxylate
  • 230301-11-8
  • Heterocycle-Pyridine series
  • CHIRAL CHEMICALS