DULCITOL

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Product Name: DULCITOL
CAS No.: 6051-87-2
Chemical Name: DULCITOL
Synonyms: BNF;BETA-NF;DULCITE;NSC 136015;MELAMPYRITE;β-Naphthoflavon;5,6-BENZOFLAVONE;B-NAPHTHOFLAVONE;β-Naphthoflavone;BetaNapthoflavone
CBNumber: CB7174209
Molecular Formula: C19H12O2
Formula Weight: 272.3
MOL File: 6051-87-2.mol

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DULCITOL Property

Melting point:: 164-166 °C (lit.)
Boiling point:: 275-280 °C (1 mmHg)
Density: 1.1382 (rough estimate)
refractive index: 1.5510 (estimate)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
form: Crystalline Powder
color: yellow to tan
BRN: 18991
LogP: 5.003 (est)
CAS DataBase Reference: 6051-87-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi,C,F
Risk Statements: 22-34-11
Safety Statements: 24/25-45-36/37/39-26-16
WGK Germany: 3
RTECS: QL6200000
F: 3-10
Hazard Note: Irritant
HS Code: 29329900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N3633
Product name: β-Naphthoflavone
Purity: ≥98%
Packaging: 1g
Price: $54.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: N3633
Product name: β-Naphthoflavone
Purity: ≥98%
Packaging: 5g
Price: $151
Updated: 2024/03/01

TCI Chemical

Product number: N0518
Product name: beta-Naphthoflavone
Purity: >99.0%(GC)
Packaging: 1g
Price: $34
Updated: 2024/03/01

TCI Chemical

Product number: N0518
Product name: beta-Naphthoflavone
Purity: >99.0%(GC)
Packaging: 5g
Price: $109
Updated: 2024/03/01

Alfa Aesar

Product number: A18543
Product name: beta-Naphthoflavone, 98+%
Packaging: 1g
Price: $36.65
Updated: 2024/03/01

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DULCITOL Chemical Properties,Usage,Production

Chemical Properties

SLIGHTLY BEIGE CRYSTALLINE POWDER

Uses

beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation.

Definition

ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.

General Description

β-Naphthoflavone is a polyaromatic hydrocarbon.

Biochem/physiol Actions

β-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors.

DULCITOL Preparation Products And Raw materials

Raw materials

Preparation Products

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6051-87-2, DULCITOLRelated Search:

Dulcitol 4'-METHOXY-5,6-BENZOFLAVONE 2-IODO-3-PHENYL-1H-NAPHTHO[2,1-B]PYRAN-1-ONE 4'-HYDROXY-BETA-NAPHTHOFLAVONE 2'-HYDROXY-BETA-NAPHTHOFLAVONE 2'-METHOXY-BETA-NAPHTHOFLAVONE 3'-METHOXY-BETA-NAPHTHOFLAVONE 3',4'-DIMETHOXY-BETA-NAPHTHOFLAVONE DULCITOL 3',4'-DIHYDROXY-BETA-NAPHTHOFLAVONE 3'-HYDROXY-B-NAPHTHOFLAVONE BETA-NAPHTHOFLAVANOL

1H-Naphtho[2,1-b]pyran-1-one,3-phenyl-

3-Phenyl-1H-benzo[f]chromen-1-one

3-Phenyl-1H-naphtho(2,1-b)pyran-1-one

3-Phenyl-1H-naphtho[2,1-b]pyran-1-one

3-Phenyl-benzo[f]chromen-1-one

β-Naphthoflavon

5,6-BENZOFLAVONE

β-Naphthoflavone, 99+%

β-Naphthoflavone 〔5,6-Benzoflavone〕

-Naphthoflavone for synthesis

MELAMPYRITE

BNF

B-NAPHTHOFLAVANONE

B-NAPHTHOFLAVONE

BETA-NAPHTHOFLAVONE

BETA-NF

DULCITE

NAPHTHOFLAVANONE, B-

NAPHTHOFLAVONE, B-

1-b)pyran-1-one,3-phenyl-1h-naphtho(

BETA-NAPHTHOFLAVONE, 98+%

BetaNapthoflavone

~-Naphthoflavone,98%

beta-Naphthoflavone, 99+%

beta-Naphthoflavone, 99+% 1GR

NAPHTHO(2,1-B)PYRAN-1-ONE,3-PHENYL-

SS-NAPHTHOFLAVONE

^b-Naphthoflavone, 98+%

NSC 136015

β-Naphthoflavone

β-Naphthoflavone|||beta-NF

6051-87-2

6051-59-1

C6H8OH6

C19H12O2

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