ChemicalBook > CAS DataBase List > 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE

Product Name: 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE
CAS No.: 14812-59-0
Chemical Name: 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE
Synonyms: 2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxa-phosphol;2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE;1,3,2-Dioxaphospholane, 2-chloro-4,4,5,5-tetramethyl-;2-Chloro-4,4,5,5-tetraMethyl-1,3,2-dioxaphospholane 95%
CBNumber: CB7178429
Molecular Formula: C6H12ClO2P
Formula Weight: 182.59
MOL File: 14812-59-0.mol

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2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE Property

Boiling point:: 81.5-82 °C13 mm Hg(lit.)
Density: 1.149 g/mL at 25 °C(lit.)
refractive index: n20/D 1.471(lit.)
Flash point:: >230 °F
InChI: InChI=1S/C6H12ClO2P/c1-5(2)6(3,4)9-10(7)8-5/h1-4H3
InChIKey: WGPCXYWWBFBNSS-UHFFFAOYSA-N
SMILES: O1C(C)(C)C(C)(C)OP1Cl

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Safety

Hazard Codes: C
Risk Statements: 14-34
Safety Statements: 22-26-27-36/37/39-45
RIDADR: UN 3265 8/PG 2
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 447536
Product name: 2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane
Purity: 95%
Packaging: 1g
Price: $233
Updated: 2025/07/31

Sigma-Aldrich

Product number: 447536
Product name: 2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane
Purity: 95%
Packaging: 5g
Price: $827
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: HCH0067215
Product name: 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE
Purity: 95.00%
Packaging: 1G
Price: $731.29
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0067215
Product name: 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE
Purity: 95.00%
Packaging: 5G
Price: $1219.42
Updated: 2021/12/16

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2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE Chemical Properties,Usage,Production

Description

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is an organic reagent commonly used in chemical and experimental research as a reagent for the phosphorylation of alcohols and heteroatoms for the formation of glycosyl donors and ligands, and in analytical studies of derivatised lignin samples. It is also used as a catalyst in CuO/TiO2 catalysed lignin oxidation studies.

Chemical Properties

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is an organic reagent in the physical state of a solid. Molecular weight: 182.59, Density: 1.149 g/cm³, Boiling point: 81.5-82° C (lit.) at 13 mmHg, Flash point: 113 °C, Refractive index: n20/D 1.471 (lit.), Store at 10°C-25°C, keep dry, under inert gas nitrogen.

Uses

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (TMDP) can be used:

As a reagent for the phosphitylation of alcohols and heteroatomic nucleophiles, resulting in the formation of useful glycosyl donors and ligands.
As a phosphitylation reagent to derivatize lignin samples for ³¹P NMR analysis.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Chloro-4,4,5,5-tetraMethyl-1,3,2-dioxaphospholane 14812-59-0
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50 tons
Release date: 2020-01-17

14812-59-0, 2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANERelated Search:

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE 2-Chloro-1,3,2-dioxaphospholane DIETHYL CHLOROPHOSPHITE

2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxa-phosphol

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE

2-Chloro-4,4,5,5-tetraMethyl-1,3,2-dioxaphospholane 95%

1,3,2-Dioxaphospholane, 2-chloro-4,4,5,5-tetramethyl-

14812-59-0

C6H12ClO2P

Phosphorus Precursors

Phosphorus Compounds

Catalysis and Inorganic Chemistry

Phosphorus Compounds

Phosphorus Precursors