ChemicalBook > CAS DataBase List > (4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester

(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester

Product Name
(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
CAS No.
472967-95-6
Chemical Name
(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
Synonyms
Atorvastatin calcium-24;Atorvastatin calcium impurity 33;(3S,5S)-Atorvastatin Acetonide tert-Butyl Ester;Atorvastatin Acetonide t-Butyl Ester (4S,6S)-Isomer;Atorvastatin Acetonide t-Butyl Ester (3S,5S)-Isomer;4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl;tert-butyl 2-[(4S,6S)-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate;tert-butyl 2-((4S,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3- phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2- dimethyl-1,3-dioxan-4-yl)acetate;(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenyl amino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid t-butyl ester;(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Este
CBNumber
CB71872425
Molecular Formula
C40H47FN2O5
Formula Weight
654.81
MOL File
472967-95-6.mol
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(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester Property

Melting point:
52-55°C
Boiling point:
678.0±55.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)
form 
Solid
pka
13.57±0.70(Predicted)
color 
Pale Yellow to Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A791770
Product name
(3S,5S)-AtorvastatinAcetonidetert-ButylEster
Packaging
10mg
Price
$300
Updated
2021/12/16
TRC
Product number
A791770
Product name
(3S,5S)-AtorvastatinAcetonidetert-ButylEster
Packaging
25mg
Price
$685
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0034031
Product name
(3S,5S)-ATORVASTATIN ACETONIDE TERT-BUTYL ESTER
Purity
95.00%
Packaging
5MG
Price
$774.4
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA18012
Product name
(3S,5S)-Atorvastatin acetonide tert-butyl ester
Packaging
25mg
Price
$841
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18394
Product name
(3S,5S)-AtorvastatinAcetonidetert-ButylEster
Packaging
1mg
Price
$990
Updated
2021/12/16
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(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

An intermediate for the preparation of (3S,5S)-Atorvastatin

(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester Suppliers

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472967-95-6, (4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl EsterRelated Search:

P-HYDROXY ATORVASTATIN LACTONE di(2-Hydroxy Atorvastatin) CalciuM Salt ATV-FX1 sodiuM salt Atorvastatin Atorvastatin Impurity 15 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide 2,3-Dehydroxy Atorvastatin Sodium Salt Atorvastatin IMpurity G O-Methyl Atorvastatin Calcium Salt Atorvastatin Impurity 46 Atorvastatin Impurity 38 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin Impurity 31 Difluoro Atorvastatin Acetonide tert-Butyl Ester Atorvastatin Dehydro Lactone Atorvastatin Impurity 20 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt Atorvastatin Oxirane Impurity

  • (3S,5S)-Atorvastatin Acetonide tert-Butyl Ester
  • (4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
  • Atorvastatin Acetonide t-Butyl Ester (3S,5S)-Isomer
  • Atorvastatin calcium-24
  • Atorvastatin impurity 23/(3S,5S)-Atorvastatin Acetonide tert-Butyl Ester/(4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
  • tert-butyl 2-[(4S,6S)-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • tert-butyl 2-((4S,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3- phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2- dimethyl-1,3-dioxan-4-yl)acetate
  • (4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenyl amino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid t-butyl ester
  • Atorvastatin Acetonide t-Butyl Ester (4S,6S)-Isomer
  • 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S,6S)-
  • 4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl
  • (4S,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Este
  • Atorvastatin calcium impurity 33
  • 472967-95-6
  • Chiral Reagents
  • Heterocycles
  • Intermediates