3,6-Dihydroxy-4-methylpyridazine
- Product Name
- 3,6-Dihydroxy-4-methylpyridazine
- CAS No.
- 5754-18-7
- Chemical Name
- 3,6-Dihydroxy-4-methylpyridazine
- Synonyms
- BUTTPARK 47\04-23;CITRACONIC HYDRAZIDE;MethylmaleicHydrazide>4-METHYLPYRIDAZINE-3,6-DIOL;4-Methyl-3,6-pyridazinediol;Methylmaleic Acid Hydrazide;4-Methyl-pyridazine-3,6-d...;3,6-DIHYDROXY-4-METHYLPYRIDAZINE;3,4-Dihydroxy-4-methylpyridazine;3,6-Dihydroxy-4-methylpyridazine, 98.5%
- CBNumber
- CB7192377
- Molecular Formula
- C5H6N2O2
- Formula Weight
- 126.11
- MOL File
- 5754-18-7.mol
3,6-Dihydroxy-4-methylpyridazine Property
- Melting point:
- 284-288 °C
- Density
- 1.226±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 9.34±0.40(Predicted)
- color
- White to Light yellow
- CAS DataBase Reference
- 5754-18-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S540862
- Product name
- 1,2-DIHYDRO-4-METHYL-3,6-PYRIDAZINEDIONE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $30.7
- Updated
- 2025/07/31
- Product number
- S540862
- Product name
- 1,2-DIHYDRO-4-METHYL-3,6-PYRIDAZINEDIONE
- Purity
- Aldrich
- Packaging
- 250mg
- Price
- $29.8
- Updated
- 2024/03/01
- Product number
- 668141
- Product name
- 3,6-Dihydroxy-4-methylpyridazine
- Purity
- 97%
- Packaging
- 1g
- Price
- $77.3
- Updated
- 2023/01/07
- Product number
- M2182
- Product name
- Methylmaleic Hydrazide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $87
- Updated
- 2024/03/01
- Product number
- M2182
- Product name
- Methylmaleic Hydrazide
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $266
- Updated
- 2024/03/01
3,6-Dihydroxy-4-methylpyridazine Chemical Properties,Usage,Production
Chemical Properties
White powder
Synthesis
616-02-4
5754-18-7
The general procedure for the synthesis of 4-methylpyridazine-3,6-dione from citraconic anhydride was as follows: citraconic anhydride (24.0 mL, 270 mmol) was slowly added dropwise to a mixture of ice-bath-cooled hydrazine (4 M aqueous solution buffered to pH 6.5 by AcOH; 200 mL) and ethanol (250 mL), and the reaction mixture appeared to be in a light-yellow heterogeneous state. Subsequently, the mixture was heated under mild reflux conditions for 24 hours. Upon completion of the reaction, the mixture was allowed to cool to room temperature and the ethanol was evaporated under reduced pressure to give a white heterophase mixture. This mixture was diluted with water (250 mL) and the resulting white precipitate was collected by filtration. The precipitate was washed with water, placed on phosphorus pentoxide and dried under vacuum at room temperature for 24 h. A white powder of 4-methylpyridazine-3,6-dione was finally obtained (21.8 g; 65% yield). The product was characterized by 1H NMR (200 MHz, DMSO-d6): δ 2.00 (3H, s), 6.85 (1H, s), 11.22 (2H, brs).
References
[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 5, p. 1644 - 1658
[2] Journal of the American Chemical Society, 1954, vol. 76, p. 4454,4457
[3] Zhurnal Obshchei Khimii, 1954, vol. 24, p. 1216,1219; engl. Ausg. S. 1205, 1206
[4] Journal of the American Chemical Society, 1954, vol. 76, p. 2201
[5] Journal of Organic Chemistry, 1954, vol. 19, p. 115,117
3,6-Dihydroxy-4-methylpyridazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,6-Dihydroxy-4-methylpyridazine manufacturers
- Product
- 3,6-Dihydroxy-4-methylpyridazine 5754-18-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-29
- Product
- 3,6-Dihydroxy-4-Methylpyridazine 5754-18-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%minHPLC
- Supply Ability
- 500kgs/month
- Release date
- 2021-11-15
- Product
- 3,6-Dihydroxy-4-methylpyridazine 5754-18-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-11-02