Description
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tert-Butanesulfinamide

Description
Product Name
tert-Butanesulfinamide
CAS No.
146374-27-8
Chemical Name
tert-Butanesulfinamide
Synonyms
2-METHYL-2-PROPANESULFINAMIDE;(S)-tert-Butanesulfinamide;2-METHYL-PROPANE-2-SULFINIC ACID AMIDE;T-BUTYLSULFINAMIDE;Methyl-2-propanesulfinaMide;S-(-)-2-Methyl-2-propanesulfinamide;tert-ButanesuL;(S)-(C4H11NOS-);ert-Butylsulfinamide;TERT-BUTYLSULPHINAMIDE
CBNumber
CB7209954
Molecular Formula
C4H11NOS
Formula Weight
121.2
MOL File
146374-27-8.mol
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tert-Butanesulfinamide Property

Melting point:
97-101 °C(lit.)
Boiling point:
220.0±23.0 °C(Predicted)
Density 
1.124
storage temp. 
2-8°C
solubility 
Soluble in methanol.
pka
10.11±0.50(Predicted)
form 
Powder or Crystals
color 
White to tan
CAS DataBase Reference
146374-27-8(CAS DataBase Reference)
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Safety

WGK Germany 
3
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
560871
Product name
2-Methyl-2-propanesulfinamide
Purity
97%, racemic
Packaging
5g
Price
$74.4
Updated
2024/03/01
Sigma-Aldrich
Product number
560871
Product name
2-Methyl-2-propanesulfinamide
Purity
97%, racemic
Packaging
1g
Price
$25
Updated
2023/06/20
TCI Chemical
Product number
B2926
Product name
tert-Butylsulfinamide
Purity
>97.0%(GC)
Packaging
1g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
B2926
Product name
tert-Butylsulfinamide
Purity
>97.0%(GC)
Packaging
5g
Price
$54
Updated
2024/03/01
Alfa Aesar
Product number
B25385
Product name
(±)-2-Methyl-2-propanesulfinamide, 97%
Packaging
1g
Price
$47.65
Updated
2024/03/01
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tert-Butanesulfinamide Chemical Properties,Usage,Production

Description

(S)-tert-Butanesulfinamide (also known as 2-Methyl-2-propanesulfinamide) is used for the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne.It can be also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine1,2-(R)-(+)-2-Methyl-2-propanesulfinamide may be used to prepare N-(1-cyclohexylmethylidene)-2-methylpropane-2-sulfinamide via copper mediated condensation with cyclohexane carboxaldehyde. It may also be used to prepare (20E)-N-[t-butyl-(R)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the development of androgen receptor antagonists. (S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents.

Chemical Properties

white to light yellow crystal powde

Uses

(±)-2-Methyl-2-propanesulfinamide is used in the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne. It is also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine.

Uses

Ellman′s Sulfinamides

tert-Butanesulfinamide Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butanesulfinamide Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from tert-Butanesulfinamide manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
tert-Butanesulfinamide 146374-27-8
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99% HPLC
Supply Ability
2000tons
Release date
2019-12-30
Hebei Chuanghai Biotechnology Co,.LTD
Product
tert-Butanesulfinamide 146374-27-8
Price
US $10.70/kg
Min. Order
10kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23
Hebei Weibang Biotechnology Co., Ltd
Product
tert-Butanesulfinamide 146374-27-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-08-13

146374-27-8, tert-ButanesulfinamideRelated Search:


  • TERT-BUTYLSULPHINAMIDE
  • T-BUTYLSULFINAMIDE
  • 2-METHYL-2-PROPANESULFINAMIDE, RACEMIC,&
  • 2-METHYL-2-PROPANESULFINAMIDE
  • 2-METHYL-PROPANE-2-SULFINIC ACID AMIDE
  • Racemic 2-Methyl-2-propanesulfinamide
  • TERT-BUTANESULFINAMIDE
  • (S)-(-)-2-METHYL-2-PROPANESULFINAMIDE, 98+%
  • 2-Methyl-2-propanesulfamide
  • (S)-tert-Butanesulfinamide
  • S-(-)-2-Methyl-2-propanesulfinamide
  • REF DUPL: (S)-(+)-t-Butylsulfinamide
  • Racemic tert Butylsulfinamide
  • Methyl-2-propanesulfinaMide
  • Ter butyl sulfinicaMide
  • (S)-(C4H11NOS-)
  • (DL)-2-Methylpropane-2-sulfinamide
  • Rac-teetbutylsulfinaMide
  • 2-Methyl-2-propanesulfinaMide, 97+%
  • 2-Propanesulfinamide, 2-methyl-
  • 2-Methyl-2-propanesulfinamide 97%, racemic
  • 2-Methylpropane-2-sulphinamide
  • <i>tert</i>-Butylsulfinamide
  • 1,1-Dimethylethylsulfinamide
  • tert-Butylsulfinamide &gt
  • tert-ButanesuL
  • (+/-)-2-Methylpropane-2-sulfinamide
  • ert-Butylsulfinamide
  • tert-Butanesulfinamide ISO 9001:2015 REACH
  • 146374-27-8
  • C4H11SON
  • CH33CSONH2
  • CHIRAL CHEMICALS
  • Organic Building Blocks
  • Sulfonamides/Sulfinamides
  • Sulfur Compounds
  • API intermediates
  • Sulphur Derivatives