ChemicalBook > CAS DataBase List > MOTILIN (HUMAN, PORCINE)
MOTILIN (HUMAN, PORCINE)
- Product Name
- MOTILIN (HUMAN, PORCINE)
- CAS No.
- 9072-41-7
- Chemical Name
- MOTILIN (HUMAN, PORCINE)
- Synonyms
- Motilin(pig);Motilin (swine);MOTILIN (HUMAN, PORCINE)
- CBNumber
- CB72130966
- Molecular Formula
- C120H188N34O35S
- Formula Weight
- 2699.04852
- MOL File
- 9072-41-7.mol
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MOTILIN (HUMAN, PORCINE) Property
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly; PBS (pH 7.2): 5 mg/ml
- form
- A crystalline solid
- Sequence
- Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Met-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 21619
- Product name
- Motilin (porcine)
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $121
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21619
- Product name
- Motilin (porcine)
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $218
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21619
- Product name
- Motilin (porcine)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $885
- Updated
- 2024/03/01
Tocris
- Product number
- 2264
- Product name
- Motilin, human, porcine
- Packaging
- 1
- Price
- $328
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2685CW
- Product name
- Humanmotilin
- Packaging
- 5mg
- Price
- $1084
- Updated
- 2021/12/16
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MOTILIN (HUMAN, PORCINE) Chemical Properties,Usage,Production
Description
Motilin is a polypeptide hormone that stimulates gastric motility through release in the small intestine and into the general circulation during fasting. In isolated rabbit duodenal segments, porcine motilin (10 nM-1 μM) induced phasic contractions and acetylcholine release from enteric neurons (EC50 = 2.5 nM). Formulations containing motilin are used to increase gastrointestinal motility in patients with diabetic gastroparesis, often in combination with erythromycin , an antibiotic and agonist at the motilin receptor.
Uses
Motilin, human, porcine is a gastrointestinal hormone, which is released during fasting and after eating, or by drinking water. Motilin, human, porcine promotes enteric cholinergic activity in human stomach with an EC50 of 33 nM, and thus modulates gastrointestinal motility function[1].
References
[1] Sanger GJ, et al., Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. Br J Pharmacol. 2013 Dec;170(7):1323-32. DOI:10.1111/bph.12075
MOTILIN (HUMAN, PORCINE) Preparation Products And Raw materials
Raw materials
Preparation Products
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