ChemicalBook > CAS DataBase List > 6-FLUOROQUINOLIN-2-AMINE

6-FLUOROQUINOLIN-2-AMINE

Product Name
6-FLUOROQUINOLIN-2-AMINE
CAS No.
791626-57-8
Chemical Name
6-FLUOROQUINOLIN-2-AMINE
Synonyms
6-FLUORO-2-QUINOLINAMINE;6-FLUOROQUINOLIN-2-AMINE;6-FLUORO-2-QUINOLINEAMINE;2-Amino-6-fluoroquinoline;2-Quinolinamine, 6-fluoro-;2-Quinolinamine,6-fluoro-(9CI)
CBNumber
CB7217706
Molecular Formula
C9H7FN2
Formula Weight
162.16
MOL File
791626-57-8.mol
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6-FLUOROQUINOLIN-2-AMINE Property

Melting point:
141-148 °C
Boiling point:
308.6±22.0 °C(Predicted)
Density 
1.315±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
5.96±0.43(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F600328
Product name
6-Fluoroquinolin-2-amine
Packaging
50mg
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0353861
Product name
6-FLUOROQUINOLIN-2-AMINE
Purity
95.00%
Packaging
5MG
Price
$502.5
Updated
2021/12/16
Labseeker
Product number
SC-66428
Product name
6-fluoroquinolin-2-amine
Purity
99
Packaging
1g
Price
$800
Updated
2021/12/16
Chemenu
Product number
CM123788
Product name
6-fluoroquinolin-2-amine
Purity
95%
Packaging
5g
Price
$1403
Updated
2021/12/16
Crysdot
Product number
CD11056145
Product name
6-Fluoroquinolin-2-amine
Purity
95+%
Packaging
5g
Price
$1485
Updated
2021/12/16
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6-FLUOROQUINOLIN-2-AMINE Chemical Properties,Usage,Production

Synthesis

742698-99-3

791626-57-8

Tert-butyl 6-fluoroquinolin-3-ylcarbamate (1.3 g, 4.95 mmol) was used as starting material, which was dissolved in 1,2-dichloroethane (15 mL), followed by trifluoroacetic acid (15 mL) and water (1 mL). The reaction mixture was stirred at room temperature for 6 hours. Upon completion of the reaction, the solvent was removed by vacuum evaporation and the residue was ground with ether. The resulting solid was purified by fast chromatography with the eluent being a 2N ammonia methanol solution in dichloromethane (gradient: 0% to 3%) to afford 6-chloroquinolin-2-amine as a colorless solid in a yield of 0.47 g (59% yield). Mass spectrometry (MS) analysis showed m/z 162.9 (MH+).

References

[1] Patent: WO2004/69792, 2004, A2. Location in patent: Page 169-170

6-FLUOROQUINOLIN-2-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-FLUOROQUINOLIN-2-AMINE Suppliers

CHEMSTEP
Tel
--
Fax
--
Email
info@chemstep.com
Country
Europe
ProdList
6143
Advantage
51
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View Lastest Price from 6-FLUOROQUINOLIN-2-AMINE manufacturers

Career Henan Chemica Co
Product
6-FLUOROQUINOLIN-2-AMINE 791626-57-8
Price
US $1.00/g
Min. Order
1g
Purity
Min98%HPLC/LC
Supply Ability
g/kg/ton Nicole258
Release date
2020-11-03