1,2-DIBENZOYLETHANE Property

Melting point:

144-145°C

Boiling point:

260 °C / 15mmHg

Density 

1.116±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

Dichloromethane (Slightly), DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

Water Solubility 

Soluble in acetone. Insoluble in water.

BRN 

782937

CAS DataBase Reference

495-71-6(CAS DataBase Reference)

NIST Chemistry Reference

1,4-Butanedione, 1,4-diphenyl-(495-71-6)

Safety

Safety Statements 

22-24/25

HS Code 

2914.39.9000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

1,2-DIBENZOYLETHANE Chemical Properties,Usage,Production

Uses

1,2-Dibenzoylethane is effective in inhibiting the in vivo mammary DMBA-DNA adduct formation. This inhibitory effect on mammary DNA adduct formation was associated with increased liver activities of glutathione S-transferase, QR, and 7-ethoxyresorufin-O-deethylase.

Uses

It is effective in inhibiting the in vivo mammary DMBA-DNA adduct formation. This inhibitory effect on mammary DNA adduct formation was associated with increased liver activities of glutathione S-transferase, QR, and 7-ethoxyresorufin-O-deethylase.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 28, p. 262, 1980 DOI: 10.1248/cpb.28.262
Journal of the American Chemical Society, 91, p. 687, 1969 DOI: 10.1021/ja01031a029
Tetrahedron Letters, 29, p. 3717, 1988 DOI: 10.1016/S0040-4039(00)82162-0