ChemicalBook > CAS DataBase List > 2-(3-Aminophenyl)acetic acid ethyl ester

2-(3-Aminophenyl)acetic acid ethyl ester

Product Name
2-(3-Aminophenyl)acetic acid ethyl ester
CAS No.
52273-79-7
Chemical Name
2-(3-Aminophenyl)acetic acid ethyl ester
Synonyms
Ethyl 2-(3-aminophenyl)acetate;Ethyl 3-aminophenylacetate;3-Amino-benzeneacetic acid ethyl ester;(3-Aminophenyl)acetic acid ethyl ester;2-(3-Aminophenyl)acetic acid ethyl ester;Benzeneacetic acid, 3-amino-, ethyl ester
CBNumber
CB72347678
Molecular Formula
C10H13NO2
Formula Weight
179.22
MOL File
52273-79-7.mol
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2-(3-Aminophenyl)acetic acid ethyl ester Property

Boiling point:
138-140 °C(Press: 3-4 Torr)
Density 
1.112±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
4.36±0.10(Predicted)
Appearance
Brown to black Liquid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
E937453
Product name
Ethyl2-(3-Aminophenyl)acetate
Packaging
100mg
Price
$60
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0398976
Product name
ETHYL-2-(3-AMINOPHENYL)ACETATE
Purity
95.00%
Packaging
5MG
Price
$495.15
Updated
2021/12/16
Acrotein
Product number
A-5958
Product name
3-Amino-benzeneaceticacidethylester
Purity
97%
Packaging
0.5g
Price
$73.33
Updated
2021/12/16
Acrotein
Product number
A-5958
Product name
3-Amino-benzeneaceticacidethylester
Purity
97%
Packaging
1g
Price
$110
Updated
2021/12/16
Crysdot
Product number
CD12065363
Product name
Ethyl2-(3-aminophenyl)acetate
Purity
95+%
Packaging
10g
Price
$317
Updated
2021/12/16
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2-(3-Aminophenyl)acetic acid ethyl ester Chemical Properties,Usage,Production

Synthesis

14318-64-0

52273-79-7

General procedure for the synthesis of ethyl 2-(3-aminophenyl)acetate from ethyl 3-nitrophenylacetate: ethyl 2-(3-nitrophenyl)acetate (3h) (1.05 g, 3.40 mmol) was dissolved in methanol (25 mL) and hydrogenation reaction was carried out for 4 h by adding 10% Pd/C (catalytic amount) as a catalyst. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target product ethyl 2-(3-aminophenyl)acetate (4h). The product was characterized by 1H-NMR (200 MHz, CDCl3): δ 1.25 (t, 3H, J = 7.2 Hz), 3.51 (s, 2H), 4.14 (q, 2H, J = 7.2 Hz), 6.59-6.71 (m, 3H), 7.11 (t, 1H, J = 7.8 Hz). The reaction was carried out quantitatively in 100% yield.

References

[1] Patent: EP3381898, 2018, A1. Location in patent: Paragraph 0200; 0265
[2] Collection of Czechoslovak Chemical Communications, 1995, vol. 60, # 4, p. 659 - 669
[3] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 3, p. 1206 - 1217
[4] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 1, p. 217 - 220
[5] Patent: US6150373, 2000, A

2-(3-Aminophenyl)acetic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(3-Aminophenyl)acetic acid ethyl ester Suppliers

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View Lastest Price from 2-(3-Aminophenyl)acetic acid ethyl ester manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
2-(3-Aminophenyl)acetic acid ethyl ester 52273-79-7
Price
US $65.00-650.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-09

52273-79-7, 2-(3-Aminophenyl)acetic acid ethyl esterRelated Search:


  • (3-Aminophenyl)acetic acid ethyl ester
  • 2-(3-Aminophenyl)acetic acid ethyl ester
  • Ethyl 3-aminophenylacetate
  • Ethyl 2-(3-aminophenyl)acetate
  • 3-Amino-benzeneacetic acid ethyl ester
  • Benzeneacetic acid, 3-amino-, ethyl ester
  • 52273-79-7