ChemicalBook > CAS DataBase List > 1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt

1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt

Product Name
1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
CAS No.
51876-97-2
Chemical Name
1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
Synonyms
AY-22284A;Alrestatin sodium;Alrestatine sodium;sodium,2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetate;1,3-Dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid sodium salt;1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
CBNumber
CB72395871
Formula Weight
0
MOL File
51876-97-2.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM1037109
Product name
SODIUM 2-(1,3-DIOXOBENZO[DE]ISOQUINOLIN-2-YL)ACETATE
Purity
95.00%
Packaging
5MG
Price
$499.32
Updated
2021/12/16
Crysdot
Product number
CD31001656
Product name
Alrestatinsodium
Purity
98+%
Packaging
5mg
Price
$55
Updated
2021/12/16
CSNpharm
Product number
CSN18314
Product name
AlrestatinSodium
Packaging
5mg
Price
$77
Updated
2021/12/16
Crysdot
Product number
CD31001656
Product name
Alrestatinsodium
Purity
98+%
Packaging
10mg
Price
$83
Updated
2021/12/16
CSNpharm
Product number
CSN18314
Product name
AlrestatinSodium
Packaging
10mg
Price
$115
Updated
2021/12/16
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1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt Chemical Properties,Usage,Production

Originator

Alrestatin,BIOMOL

Uses

Enzyme inhibitor (aldose reductase).

Manufacturing Process

1,3-Dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid:
1,8-Naphthalic acid anhydride (110 g, 0.556 mole), glycine (48 g, 0.64 mole) and dimethylformamide (750 ml) are heated and stirred at reflux for 2 hr. The homogeneous dark solution is cooled to about 100°C and 750 ml of hot water is added slowly to the stirred solution. The reaction mixture is cooled and allowed to stand in a refrigerator for 16 hr. The precipitate is collected and recrystallized from ethanol, using decolorizing charcoal, to give the title compound, MP: 271°-272°C.
In practice it is usually used as sodium salt.

Therapeutic Function

Aldose reductase inhibitor

1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt Suppliers

Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58

51876-97-2, 1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium saltRelated Search:


  • 1,3-Dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid sodium salt
  • 1,3-Dioxo-1H-benzo[de]isoquinoline-2(3H)-acetic acid sodium salt
  • Alrestatin sodium
  • AY-22284A
  • sodium,2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetate
  • Alrestatine sodium
  • 51876-97-2