4-(CHLOROMETHYL)PHENYL ISOCYANATE Property

Melting point:

32-33 °C(lit.)

Boiling point:

115-117°C 10mm

Density 

1.216 g/mL at 25 °C(lit.)

refractive index 

1.5570 (estimate)

Flash point:

>230 °F

storage temp. 

2-8°C

Sensitive 

Moisture Sensitive

BRN 

2828900

Safety

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

7-26-27-37/39

RIDADR 

2928

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

29291000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-(CHLOROMETHYL)PHENYL ISOCYANATE Chemical Properties,Usage,Production

Chemical Properties

YELLOW LOW MELTING SOLID

Uses

4-(Chloromethyl)phenyl isocyanate may be used in the synthesis of series of carbamate derivatives of Hoechst 33258, potential anticancer agents.

General Description

4-(Chloromethyl)phenyl isocyanate is an aryl isocyanate. It is reported to participate in the anomeric O-acylation of Kdo.