2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE Property

Boiling point:

162-163 °C/768 mmHg (lit.)

Density 

0.899 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.453(lit.)

Flash point:

110 °F

storage temp. 

2-8°C

solubility 

Chloroform, Methanol (Slightly)

form 

Oil

color 

Clear Colourless

Specific Gravity

0.899

Hydrolytic Sensitivity

4: no reaction with water under neutral conditions

BRN 

1747038

Stability:

Moisture Sensitive

Safety

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-36

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

TSCA 

No

HazardClass 

3.2

PackingGroup 

III

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE Chemical Properties,Usage,Production

Uses

2-??(Chloromethyl)??allyl-??trimethylsilane is one of the reagents to synthesize Leucasandrolide A Macrolide (I) via Mukaiyama aldol coupling.2-??(Chloromethyl)??allyl-??trimethylsilane was used in catalytic Sakurai reaction of a,??b-??enones.