8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER

Product Name: 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
CAS No.: 250685-44-0
Chemical Name: 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER
Synonyms: NNC 63-0532;methyl [8-(1-naphthylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetate;methyl 2-(8-(naphthalen-2-ylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)acetate;methyl 2-[8-(naphthalen-1-ylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetate;8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER;NNC 63-0532. methyl [8-(1-naphthylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetate;1,3,8-Triazaspiro[4.5]decane-3-aceticacid, 8-(1-naphthalenylmethyl)-4-oxo-1-phenyl-, methyl ester
CBNumber: CB7244269
Molecular Formula: C27H29N3O3
Formula Weight: 443.54
MOL File: 250685-44-0.mol

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8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER Property

storage temp.: Store at RT
solubility: Soluble to 5 mM in ethanol and to 50 mM in DMSO
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1780
Product name: NNC63-0532
Purity: ≥98%(HPLC)
Packaging: 10
Price: $233
Updated: 2021/12/16

Tocris

Product number: 1780
Product name: NNC63-0532
Purity: ≥98%(HPLC)
Packaging: 50
Price: $961
Updated: 2021/12/16

Usbiological

Product number: 256009
Product name: NNC 63-0532
Packaging: 10mg
Price: $495
Updated: 2021/12/16

TRC

Product number: N372970
Product name: 8-(1-Naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-aceticacidMethylEster
Packaging: 100mg
Price: $165
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009862
Product name: NNC 63-0532
Purity: 95.00%
Packaging: 1G
Price: $173.67
Updated: 2021/12/16

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8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER Chemical Properties,Usage,Production

Uses

8-(1-Naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetic acid Methyl Ester is a potent nociceptin receptor agonist.

Biological Activity

Potent non-peptide agonist for the NOP receptor (EC 50 = 305 nM, K i = 7.3 nM); ~ 12-fold selective over other receptors. Centrally active following systemic administration in vivo .

storage

Store at RT

8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER Suppliers

China 21 Germany 2 India 1 United Kingdom 1 United States 7 Global 32

Tocris Bioscience

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250685-44-0, 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTERRelated Search:

1-(1-BENZYLPIPERIDIN-4-YL)-N-METHYLMETHANAMINE N-BENZYL-4-AMINO-PIPERIDINE-4-CARBOXAMIDE PIPERIDINE-4-CARBOXYLIC ACID (2-METHOXY-ETHYL)-AMIDE 8-benzyl-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one 8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER

NNC 63-0532

8-(1-NAPHTHALENYLMETHYL)-4-OXO-1-PHENYL-1,3,8-TRIAZASPIRO[4.5]DECANE-3-ACETIC ACID, METHYL ESTER

methyl 2-[8-(naphthalen-1-ylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetate

1,3,8-Triazaspiro[4.5]decane-3-aceticacid, 8-(1-naphthalenylmethyl)-4-oxo-1-phenyl-, methyl ester

methyl 2-(8-(naphthalen-2-ylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)acetate

methyl [8-(1-naphthylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetate

NNC 63-0532. methyl [8-(1-naphthylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetate

250685-44-0

Opioid receptor and opioid-like receptor