4-(2-FLUOROPHENYL)BUTANOIC ACID

Product Name: 4-(2-FLUOROPHENYL)BUTANOIC ACID
CAS No.: 143654-62-0
Chemical Name: 4-(2-FLUOROPHENYL)BUTANOIC ACID
Synonyms: 2-Fluoro-benzenebutanoic acid;4-(2-FLUOROPHENYL)BUTANOIC ACID;Benzenebutanoic acid, 2-fluoro-;4-(2-Fluoro-phenyl)-butyric acid
CBNumber: CB72448553
Molecular Formula: C10H11FO2
Formula Weight: 182.19
MOL File: 143654-62-0.mol

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4-(2-FLUOROPHENYL)BUTANOIC ACID Property

Boiling point:: 291.7±15.0 °C(Predicted)
Density: 1.182±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.71±0.10(Predicted)
Appearance: pale yellow solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F588948
Product name: 4-(2-fluorophenyl)butanoicacid
Packaging: 50mg
Price: $200
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2721-3-1Q
Product name: 4-(2-Fluorophenyl)butanoic acid
Packaging: 250mg
Price: $405
Updated: 2021/12/16

AK Scientific

Product number: 2505AL
Product name: 4-(2-Fluorophenyl)butanoicacid
Packaging: 1g
Price: $454
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0046843
Product name: 4-(2-FLUORO-PHENYL)-BUTYRIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $495.35
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2721-3-1Q
Product name: 4-(2-Fluorophenyl)butanoic acid
Packaging: 1g
Price: $525
Updated: 2021/12/16

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4-(2-FLUOROPHENYL)BUTANOIC ACID Chemical Properties,Usage,Production

Synthesis

911825-55-3

143654-62-0

Procedure for the synthesis of 4-(2-fluorophenyl)butyric acid (31): 1.79 g of 2-(4-methylbutanoic acid)fluorobenzene (cas:911825-55-3) was added to a round-bottomed flask, which was dissolved in 17 mL of methanol. To this solution was added 1 g of aqueous sodium hydroxide. The reaction mixture was stirred at room temperature for 20 hours. After the reaction was completed, the solvent was removed by evaporation and the crude product was diluted with 15 mL of 0.5 M hydrochloric acid. It was extracted three times with dichloromethane, the organic phases were combined, dried and concentrated to give 1.17 g (92% yield) of the target product 4-(2-fluorophenyl)butyric acid (31).

References

[1] Patent: WO2006/108103, 2006, A1. Location in patent: Page/Page column 33-34
[2] Patent: US2008/119496, 2008, A1. Location in patent: Page/Page column 12
[3] Patent: WO2008/60301, 2008, A1. Location in patent: Page/Page column 32-33

4-(2-FLUOROPHENYL)BUTANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-FLUOROPHENYL)BUTANOIC ACID Suppliers

China 19 India 1 United States 3 Global 23

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143654-62-0, 4-(2-FLUOROPHENYL)BUTANOIC ACIDRelated Search:

BOC-(S)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRIC ACID FMOC-(R)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRIC ACID (S)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE 3-(2',4'-DIFLUOROBENZOYL)PROPIONIC ACID FMOC-(S)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRIC ACID (R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE BOC-(R)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRIC ACID FMOC-(R)-3-AMINO-4-(PENTAFLUORO-PHENYL)-BUTYRIC ACID 4-(2,6-DIFLUOROPHENYL)-4-OXOBUTYRIC ACID BOC-(R)-3-AMINO-4-(PENTAFLUORO-PHENYL)-BUTYRIC ACID (R)-3-AMINO-4-PENTAFLUOROPHENYLBUTANOIC ACID HYDROCHLORIDE 4-(2-FLUORO-PHENYL)-4-OXO-BUTYRIC ACID 4-(2,5-difluorophenyl)-4-oxobutanoic acid 4-(2,3-DIFLUOROPHENYL)-4-OXOBUTYRIC ACID ETHYL 4-(2,4-DIFLUOROPHENYL)-4-OXOBUTYRATE ETHYL 4-(2,3-DIFLUOROPHENYL)-4-OXOBUTYRATE ETHYL 4-(2,5-DIFLUOROPHENYL)-4-OXOBUTYRATE 4-FLUORO-3-OXO-1-PHENYL-1-INDANECARBOXYLIC ACID

Benzenebutanoic acid, 2-fluoro-

4-(2-Fluoro-phenyl)-butyric acid

2-Fluoro-benzenebutanoic acid

4-(2-FLUOROPHENYL)BUTANOIC ACID

143654-62-0