ChemicalBook > CAS DataBase List > CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA

Product Name: CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA
CAS No.: 165454-06-8
Chemical Name: CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA
Synonyms: CBZ-AEEA;3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid;CBZ-AEEA.DCHA;Cb-NH-PEG2-CH2COOH;CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA;2-[2-(Cbz-amino)ethoxy]ethoxyacetic acid;CBZ- 8 -AMINO- 3 , 6 - DIOXA-CTANOIC ACID DCHA;8-Benzyloxycarbonylamino-3,6-dioxaoctanoic acid;3,6,11-Trioxa-9-azadodecanoic acid, 10-oxo-12-phenyl-;dicyclohexylammonium 3-oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oate
CBNumber: CB72449550
Molecular Formula: C14H19NO6
Formula Weight: 297.3
MOL File: 165454-06-8.mol

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CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA Property

Boiling point:: 506.6±45.0 °C(Predicted)
Density: 1.233±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 3.40±0.10(Predicted)
form: Viscous Liquid
color: Colorless to light yellow
InChI: InChI=1S/C14H19NO6/c16-13(17)11-20-9-8-19-7-6-15-14(18)21-10-12-4-2-1-3-5-12/h1-5H,6-11H2,(H,15,18)(H,16,17)
InChIKey: GWUWSVXMAZFFNT-UHFFFAOYSA-N
SMILES: C(O)(=O)COCCOCCNC(=O)OCC1=CC=CC=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemPep

Product number: 280301
Product name: Z-NH-PEG2-CH2COOH
Packaging: 1g
Price: $250
Updated: 2021/12/16

ChemPep

Product number: 280301
Product name: Z-NH-PEG2-CH2COOH
Packaging: 5g
Price: $558
Updated: 2021/12/16

purepeg

Product number: 4322602
Product name: CBZ-8-amino-3,6-dioxaoctanoicacid;CBZ-AEEA
Purity: min.97%
Packaging: 5G
Price: $625
Updated: 2021/12/16

Chemenu

Product number: CM250115
Product name: 3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oicacid
Purity: 95%
Packaging: 10g
Price: $701
Updated: 2021/12/16

Alichem

Product number: 165454068
Product name: 3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oicacid
Packaging: 10g
Price: $780
Updated: 2021/12/16

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CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA Chemical Properties,Usage,Production

Uses

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA Preparation Products And Raw materials

Raw materials

Preparation Products

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165454-06-8, CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHARelated Search:

Z-NH-PEG8-CH2CH2COOH Z-12-aMino-4,7,10-trioxadodecanoic acid Z-NH-PEG10-CH2CH2COOH Z-21-aMino-4,7,10,13,16,19-hexaoxaheneicosanoic acid Z-NH-5(ethylene glycol)-acetic acid Z-NH-8(ethylene glycol)-acetic acid Z-18-aMino-4,7,10,13,16-pentaoxaoctadecanoic acid Z-NH-PEG12-CH2CH2COOH (2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID BENZYL ESTER CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA

3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid

CBZ-AEEA

CBZ-AEEA.DCHA

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA

Cb-NH-PEG2-CH2COOH

2-[2-(Cbz-amino)ethoxy]ethoxyacetic acid

8-Benzyloxycarbonylamino-3,6-dioxaoctanoic acid

3,6,11-Trioxa-9-azadodecanoic acid, 10-oxo-12-phenyl-

PROTAC Linkers,Cbz-NH-PEG-2-CH2COOH,Cbz NH PEG2 CH2COOH,Inhibitor,CbzNHPEG2CH2COOH,inhibit

CBZ- 8 -AMINO- 3 , 6 - DIOXA-CTANOIC ACID DCHA

dicyclohexylammonium 3-oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oate

165454-06-8