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5-HYDROXY ISATIN

Product Name
5-HYDROXY ISATIN
CAS No.
116569-09-6
Chemical Name
5-HYDROXY ISATIN
Synonyms
5-HYDROXY ISATIN;Flumazenil Impurity 17;5-hydroxyindoline-2,3-dione;5-Hydroxy-1H-indole-2,3-dione;1H-Indole-2,3-dione, 5-hydroxy-;5-hydroxy-2,3-dihydro-1H-indole-2,3-dione;5-Hydroxy isatin 5-Hydroxy indole-2,3-dione
CBNumber
CB72455151
Molecular Formula
C8H5NO3
Formula Weight
163.13
MOL File
116569-09-6.mol
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5-HYDROXY ISATIN Property

storage temp. 
-20°C
solubility 
DMF: 3 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form 
A solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

AK Scientific
Product number
6895CR
Product name
5-Hydroxyindoline-2,3-dione
Packaging
2mg
Price
$218
Updated
2021/12/16
AK Scientific
Product number
6895CR
Product name
5-Hydroxyindoline-2,3-dione
Packaging
25mg
Price
$334
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0386196
Product name
5-HYDROXYISATIN
Purity
95.00%
Packaging
5MG
Price
$496.32
Updated
2021/12/16
AK Scientific
Product number
6895CR
Product name
5-Hydroxyindoline-2,3-dione
Packaging
2.5g
Price
$2895
Updated
2021/12/16
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5-HYDROXY ISATIN Chemical Properties,Usage,Production

Biological Activity

5-hydroxy Isatin is an inhibitor of monoamine oxidase A (MAO-A; IC50 = 8.4 μM).1 It is selective for MAO-A over MAO-B (IC50 = >100 μM). 5-hydroxy Isatin (50 μM) also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.2

References

1.Medvedev, A.E., Goodwin, B., Chow, A., et al.Inhibitory potency of some isatin analogues on human monoamine oxidase A and BBiochem. Pharmacol.44(3)590-592(1992) 2.Medvedev, A.E., Goodwin, B.L., Sandler, M., et al.Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclaseBiochem. Pharmacol.57(8)913-915(1999)

5-HYDROXY ISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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5-HYDROXY ISATIN Suppliers

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116569-09-6, 5-HYDROXY ISATINRelated Search:


  • 5-HYDROXY ISATIN
  • 5-Hydroxy-1H-indole-2,3-dione
  • 5-hydroxyindoline-2,3-dione
  • 5-Hydroxy isatin 5-Hydroxy indole-2,3-dione
  • 1H-Indole-2,3-dione, 5-hydroxy-
  • 5-hydroxy-2,3-dihydro-1H-indole-2,3-dione
  • Flumazenil Impurity 17
  • 116569-09-6