5-HYDROXY ISATIN

Product Name: 5-HYDROXY ISATIN
CAS No.: 116569-09-6
Chemical Name: 5-HYDROXY ISATIN
Synonyms: 5-HYDROXY ISATIN;Flumazenil Impurity 17;5-hydroxyindoline-2,3-dione;5-Hydroxy-1H-indole-2,3-dione;1H-Indole-2,3-dione, 5-hydroxy-;5-hydroxy-2,3-dihydro-1H-indole-2,3-dione;5-Hydroxy isatin 5-Hydroxy indole-2,3-dione
CBNumber: CB72455151
Molecular Formula: C8H5NO3
Formula Weight: 163.13
MOL File: 116569-09-6.mol

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5-HYDROXY ISATIN Property

storage temp.: -20°C
solubility: DMF: 3 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form: A solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

AK Scientific

Product number: 6895CR
Product name: 5-Hydroxyindoline-2,3-dione
Packaging: 2mg
Price: $218
Updated: 2021/12/16

AK Scientific

Product number: 6895CR
Product name: 5-Hydroxyindoline-2,3-dione
Packaging: 25mg
Price: $334
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0386196
Product name: 5-HYDROXYISATIN
Purity: 95.00%
Packaging: 5MG
Price: $496.32
Updated: 2021/12/16

AK Scientific

Product number: 6895CR
Product name: 5-Hydroxyindoline-2,3-dione
Packaging: 2.5g
Price: $2895
Updated: 2021/12/16

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5-HYDROXY ISATIN Chemical Properties,Usage,Production

Uses

5-Hydroxyisatin can be used to synthesize anti-cancer agents[1].

Biological Activity

5-hydroxy Isatin is an inhibitor of monoamine oxidase A (MAO-A; IC50 = 8.4 μM).1 It is selective for MAO-A over MAO-B (IC50 = >100 μM). 5-hydroxy Isatin (50 μM) also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.2

References

1.Medvedev, A.E., Goodwin, B., Chow, A., et al.Inhibitory potency of some isatin analogues on human monoamine oxidase A and BBiochem. Pharmacol.44(3)590-592(1992) 2.Medvedev, A.E., Goodwin, B.L., Sandler, M., et al.Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclaseBiochem. Pharmacol.57(8)913-915(1999)

5-HYDROXY ISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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5-HYDROXY ISATIN Suppliers

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116569-09-6, 5-HYDROXY ISATINRelated Search:

5-Methoxyisatin 5-(TRIFLUOROMETHOXY)ISATIN AKOS BBS-00005462 AKOS BBS-00005463 5-METHOXY-1-METHYL-1H-INDOLE-2,3-DIONE AKOS BBS-00005457 5-ethoxy-1H-indole-2,3-dione AKOS BBS-00005984 AKOS BBS-00005453 AKOS BBS-00005981 AKOS BBS-00005975 1-[2-(2-CHLORO-ETHOXY)-ETHYL]-5-METHOXY-1H-INDOLE-2,3-DIONE AKOS BBS-00005983 5-phenoxy-1H-indole-2,3-dione AKOS BBS-00005976 AKOS BBS-00005977 AKOS BBS-00005978 1-(6-CHLOROHEXYL)-5-METHOXY-1H-INDOLE-2,3-DIONE

5-HYDROXY ISATIN

5-Hydroxy-1H-indole-2,3-dione

5-hydroxyindoline-2,3-dione

5-Hydroxy isatin 5-Hydroxy indole-2,3-dione

1H-Indole-2,3-dione, 5-hydroxy-

5-hydroxy-2,3-dihydro-1H-indole-2,3-dione

Flumazenil Impurity 17

116569-09-6