ChemicalBook > CAS DataBase List > 4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE

Product Name
4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE
CAS No.
1072895-86-3
Chemical Name
4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE
Synonyms
4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE;1H-Pyrazolo[3,4-d]pyrimidine, 4,6-dichloro-1,3-dimethyl-
CBNumber
CB72466575
Molecular Formula
C7H6Cl2N4
Formula Weight
217.06
MOL File
1072895-86-3.mol
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4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Property

Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
0.09±0.30(Predicted)
form 
solid
color 
White
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D439888
Product name
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine
Packaging
10mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-Q2
Product name
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine
Packaging
250mg
Price
$218
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0365340
Product name
4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE
Purity
95.00%
Packaging
5MG
Price
$498.16
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-Q2
Product name
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine
Packaging
1g
Price
$512
Updated
2021/12/16
Apolloscientific
Product number
OR30659
Product name
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine
Packaging
1g
Price
$464
Updated
2021/12/16
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4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Chemical Properties,Usage,Production

Synthesis

1072895-79-4

1072895-86-3

1,3-Dimethyl-1,7-dihydro-pyrazolo[3,4-d]pyrimidine-4,6-dione (1 g, 5.56 mmol) was used as starting material and mixed with phosphorus pentachloride (3.47 g, 3 equiv.) in phosphorus trichloride (20 mL). The reaction mixture was heated to reflux for 18 hours. Upon completion of the reaction, the excess phosphorous trichloride was removed by distillation under reduced pressure. The residue was carefully poured onto ice and extracted with dichloromethane (3 x 20 mL). The organic phases were combined and purified by column chromatography to give 4,6-dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine (680 mg, 63% yield) as a final product as a beige solid.

References

[1] Patent: WO2009/97446, 2009, A1. Location in patent: Page/Page column 65; 66
[2] Tetrahedron Letters, 2008, vol. 49, # 42, p. 6081 - 6083

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Suppliers

China 19 Germany 1 India 1 United Kingdom 1 United States 6 Global 28
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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United States
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777
Fax
+86-25-83453306
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info@chemlin.com.cn
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China
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NovoChemy Ltd.
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Amadis Chemical Company Limited
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Aikon International Limited
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1072895-86-3, 4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINERelated Search:


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