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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER

Product Name
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER
CAS No.
38074-72-5
Chemical Name
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER
Synonyms
vildagliptin Impurity U;Vildagliptin Impurity 68;Vildagliptin Impurity 78;Vildagliptin Impurity 13;chloroacetyl L-proline methyl ester;Methyl (2-chloroacetyl)-L-prolinate;N-Chloroacetyl-L-proline Methyl Ester;1-(CHLOROACETYL)-L-PROLINE METHYL ESTER;L-Proline, 1-(2-chloroacetyl)-, methyl ester;Vildagliptin Impurity-78/Vildagliptin Impurity-I
CBNumber
CB72466999
Molecular Formula
C8H12ClNO3
Formula Weight
205.64
MOL File
38074-72-5.mol
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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Property

Boiling point:
316.2±37.0 °C(Predicted)
Density 
1.285±0.06 g/cm3(Predicted)
pka
-3.02±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Chemical Properties,Usage,Production

Uses

N-Chloroacetyl-L-proline Methyl Ester is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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38074-72-5, 1-(CHLOROACETYL)-L-PROLINE METHYL ESTERRelated Search:


  • 1-(CHLOROACETYL)-L-PROLINE METHYL ESTER
  • Vildagliptin Impurity 13
  • Vildagliptin Impurity 10/Methyl (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylate
  • chloroacetyl L-proline methyl ester
  • vildagliptin Impurity U
  • Vildagliptin Impurity 78
  • L-Proline, 1-(2-chloroacetyl)-, methyl ester
  • (S)-methyl 1-(2-chloroacetyl)pyrrolidine-2-carboxylate
  • N-Chloroacetyl-L-proline Methyl Ester
  • (2S,2'S)-1,1'-(2,2'-(((3R,5R,7R)-adamantan-1-yl)azanediyl)bis(acetyl))bis(pyrrolidine-2-carbonitrile) hydrochloride
  • Vildagliptin Impurity 68
  • Vildagliptin Impurity-78/Vildagliptin Impurity-I
  • Vildagliptin Impurity-IQ: What is Vildagliptin Impurity-I Q: What is the CAS Number of Vildagliptin Impurity-I Q: What are the applications of Vildagliptin Impurity-I
  • Methyl (2-chloroacetyl)-L-prolinate
  • (S)-methyl 1-(2-chloroacetyl)pyrrolidine-2-carboxylate? (Vildagliptin Impurity)
  • (2S,2'S)-1,1'-(2,2'-(((3R,5R,7R)-adamantan-1-yl)azanediyl)bis(acetyl)) bis(pyrrolidine-2-carbonitrile) hydrochloride
  • 38074-72-5