ChemicalBook > CAS DataBase List > Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate

Product Name
Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
CAS No.
571189-16-7
Chemical Name
Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
Synonyms
tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate;4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester;Palbociclib Impurity 111;1-Boc-4-(6-Nitro-3-Pyridyl)Piperazine;1-BOC-4-(6-NITROPYRIDIN-3-YL)PIPERAZINE;1-Boc-4-(6-nitropyridin-3-yl)piperazime;4-(6-Nitropyridin-3-yl)piperazine, N1-Boc protected;4-(6-Nitropyridin-3-yl)piperazine, N1-BOC protected 97%;Tert. butyl-4-(6-Nitropyridin-3-yl)piperazino-1-carboxylate;4-(6-nitropyridin-3-yl)-1-piperazinecarboxylic acid tert-butyl ester
CBNumber
CB72467082
Molecular Formula
C14H20N4O4
Formula Weight
308.33
MOL File
571189-16-7.mol
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Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate Property

Boiling point:
480.1±45.0 °C(Predicted)
Density 
1.258
storage temp. 
Inert atmosphere,Room Temperature
pka
0.11±0.70(Predicted)
InChI
InChI=1S/C14H20N4O4/c1-14(2,3)22-13(19)17-8-6-16(7-9-17)11-4-5-12(15-10-11)18(20)21/h4-5,10H,6-9H2,1-3H3
InChIKey
SUWKOEMQNOBJEQ-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCN(C2=CC=C([N+]([O-])=O)N=C2)CC1
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H54465
Product name
1-Boc-4-(6-nitro-3-pyridyl)piperazine, 97%
Packaging
1g
Price
$146
Updated
2024/03/01
Alfa Aesar
Product number
H54465
Product name
1-Boc-4-(6-nitro-3-pyridyl)piperazine, 97%
Packaging
5g
Price
$516
Updated
2024/03/01
Alfa Aesar
Product number
H54465
Product name
1-Boc-4-(6-nitro-3-pyridyl)piperazine, 97%
Packaging
250mg
Price
$38.5
Updated
2021/12/16
TRC
Product number
B810175
Product name
tert-Butyl4-(6-Nitropyridin-3-yl)piperazine-1-carboxylate
Packaging
1g
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR54564
Product name
4-(6-Nitropyridin-3-yl)piperazine,N1-BOCprotected
Purity
97%
Packaging
5g
Price
$89
Updated
2021/12/16
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Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate Chemical Properties,Usage,Production

Description

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate is a pharmaceutical intermediate compound that can be used to synthesize the anticancer drug Palbociclib. Palbociclib is used to treat estrogen receptor-positive (ER+) and human epidermal growth factor receptor-negative (HER2-) breast cancer.

Uses

tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate is used in preparation of Heterocyclic compound as cdk-hdac double-channel inhibitor.

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate manufacturers

Changzhou Rokechem Technology Co., Ltd.
Product
Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 571189-16-7
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
98%；USP/EP/CP
Supply Ability
1-10000kgs
Release date
2023-06-14
Career Henan Chemical Co
Product
1-BOC-4-(6-NITROPYRIDIN-3-YL)PIPERAZINE 571189-16-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-25

571189-16-7, Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylateRelated Search:

2-Cyanopyridine

  • 1-BOC-4-(6-NITROPYRIDIN-3-YL)PIPERAZINE
  • tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
  • 4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester
  • 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester
  • NaMe:4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester
  • Tert. butyl-4-(6-Nitropyridin-3-yl)piperazino-1-carboxylate
  • 1-Piperazinecarboxylic acid, 4-(6-nitro-3-pyridinyl)-, 1,1-diMethylethyl ester
  • 4-(6-nitro-3-pyridinyl)-1-piperazinecarboxylic acid,1,1-dimethylethyl ester
  • 4-(6-Nitropyridin-3-yl)piperazine, N1-Boc protected
  • 4-(6-nitropyridin-3-yl)-1-piperazinecarboxylic acid tert-butyl ester
  • 1-Boc-4-(6-Nitro-3-Pyridyl)Piperazine
  • 4-(6-Nitropyridin-3-yl)piperazine, N1-BOC protected 97%
  • 1-Boc-4-(6-nitropyridin-3-yl)piperazime
  • Palbociclib Impurity 111
  • 571189-16-7
  • Anticancer