4-Iodopyrimidin-2-amine
- Product Name
- 4-Iodopyrimidin-2-amine
- CAS No.
- 815610-16-3
- Chemical Name
- 4-Iodopyrimidin-2-amine
- Synonyms
- 4-Iodopyrimidin-2-amine;2-Amino-4-iodopyrimidine;2-Pyrimidinamine, 4-iodo-;4-Iodo-pyrimidin-2-ylamine;4-Iodopyrimidin-2-amine ISO 9001:2015 REACH
- CBNumber
- CB72470132
- Molecular Formula
- C4H4IN3
- Formula Weight
- 221
- MOL File
- 815610-16-3.mol
4-Iodopyrimidin-2-amine Property
- Boiling point:
- 364.9±34.0 °C(Predicted)
- Density
- 2.204±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.27±0.10(Predicted)
- Appearance
- Off-white to light brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A579048
- Product name
- 2-Amino-4-iodopyrimidine
- Packaging
- 500mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- HCH0363006
- Product name
- 2-AMINO-4-IODOPYRIMIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.05
- Updated
- 2021/12/16
- Product number
- W8589
- Product name
- 2-Amino-4-iodopyrimidine
- Packaging
- 5g
- Price
- $564
- Updated
- 2021/12/16
- Product number
- 123599
- Product name
- 2-Amino-4-iodopyrimidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1073
- Updated
- 2021/12/16
- Product number
- 61-1641
- Product name
- 4-iodopyrimidin-2-amine
- Purity
- 95-98%
- Packaging
- 1g
- Price
- $720
- Updated
- 2021/12/16
4-Iodopyrimidin-2-amine Chemical Properties,Usage,Production
Synthesis
3993-78-0
815610-16-3
The general procedure for the synthesis of 2-amino-4-iodopyrimidine using 2-amino-4-chloropyrimidine as starting material was as follows: 2-amino-4-chloropyrimidine (13.0 g, 100 mmol) was slowly added to 57 wt% aqueous hydriodic acid solution (115 mL, 1.00 mol) at 0 °C. The reaction mixture was stirred continuously for 3 hours at room temperature. Subsequently, the mixture was cooled to 0 °C and the resulting precipitate was removed by filtration. The filter cake was transferred to a pre-cooled aqueous 5 N Na2CO3 solution (200 mL). The aqueous phase was extracted using ethyl acetate (3 × 500 mL), and the combined organic phases were concentrated under reduced pressure to afford 2-amino-4-iodopyrimidine (21.1 g, 95.0 mmol, 95% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 7.78 (d, J = 5.0 Hz, 1H), 7.02 (br.s, 2H), 7.00 (d, J = 5.0 Hz, 1H). The mass spectrum (ESI, cation mode) showed m/z: 222.1 ([M + H]+).
References
[1] European Journal of Medicinal Chemistry, 2014, vol. 80, p. 364 - 382
[2] Organic Letters, 2014, vol. 16, # 3, p. 708 - 711
4-Iodopyrimidin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Iodopyrimidin-2-amine manufacturers
- Product
- 4-Iodopyrimidin-2-amine 815610-16-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-06
- Product
- 4-Iodopyrimidin-2-amine 815610-16-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 4-Iodopyrimidin-2-amine 815610-16-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09