ChemicalBook > CAS DataBase List > 4-Iodopyrimidin-2-amine

4-Iodopyrimidin-2-amine

Product Name
4-Iodopyrimidin-2-amine
CAS No.
815610-16-3
Chemical Name
4-Iodopyrimidin-2-amine
Synonyms
4-Iodopyrimidin-2-amine;2-Amino-4-iodopyrimidine;2-Pyrimidinamine, 4-iodo-;4-Iodo-pyrimidin-2-ylamine;4-Iodopyrimidin-2-amine ISO 9001：2015 REACH
CBNumber
CB72470132
Molecular Formula
C4H4IN3
Formula Weight
221
MOL File
815610-16-3.mol
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4-Iodopyrimidin-2-amine Property

Boiling point:
364.9±34.0 °C(Predicted)
Density 
2.204±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
3.27±0.10(Predicted)
Appearance
Off-white to light brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A579048
Product name
2-Amino-4-iodopyrimidine
Packaging
500mg
Price
$330
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0363006
Product name
2-AMINO-4-IODOPYRIMIDINE
Purity
95.00%
Packaging
5MG
Price
$505.05
Updated
2021/12/16
AK Scientific
Product number
W8589
Product name
2-Amino-4-iodopyrimidine
Packaging
5g
Price
$564
Updated
2021/12/16
Matrix Scientific
Product number
123599
Product name
2-Amino-4-iodopyrimidine
Purity
95+%
Packaging
1g
Price
$1073
Updated
2021/12/16
Abosyn
Product number
61-1641
Product name
4-iodopyrimidin-2-amine
Purity
95-98%
Packaging
1g
Price
$720
Updated
2021/12/16
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4-Iodopyrimidin-2-amine Chemical Properties,Usage,Production

Synthesis

3993-78-0

815610-16-3

The general procedure for the synthesis of 2-amino-4-iodopyrimidine using 2-amino-4-chloropyrimidine as starting material was as follows: 2-amino-4-chloropyrimidine (13.0 g, 100 mmol) was slowly added to 57 wt% aqueous hydriodic acid solution (115 mL, 1.00 mol) at 0 °C. The reaction mixture was stirred continuously for 3 hours at room temperature. Subsequently, the mixture was cooled to 0 °C and the resulting precipitate was removed by filtration. The filter cake was transferred to a pre-cooled aqueous 5 N Na2CO3 solution (200 mL). The aqueous phase was extracted using ethyl acetate (3 × 500 mL), and the combined organic phases were concentrated under reduced pressure to afford 2-amino-4-iodopyrimidine (21.1 g, 95.0 mmol, 95% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 7.78 (d, J = 5.0 Hz, 1H), 7.02 (br.s, 2H), 7.00 (d, J = 5.0 Hz, 1H). The mass spectrum (ESI, cation mode) showed m/z: 222.1 ([M + H]+).

References

[1] European Journal of Medicinal Chemistry, 2014, vol. 80, p. 364 - 382
[2] Organic Letters, 2014, vol. 16, # 3, p. 708 - 711

4-Iodopyrimidin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Iodopyrimidin-2-amine Suppliers

China 59 India 2 United Kingdom 1 United States 5 Global 67
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
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View Lastest Price from 4-Iodopyrimidin-2-amine manufacturers

Dideu Industries Group Limited
Product
4-Iodopyrimidin-2-amine 815610-16-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-06
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Iodopyrimidin-2-amine 815610-16-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Iodopyrimidin-2-amine 815610-16-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

815610-16-3, 4-Iodopyrimidin-2-amineRelated Search:


  • 4-Iodopyrimidin-2-amine
  • 2-Amino-4-iodopyrimidine
  • 4-Iodo-pyrimidin-2-ylamine
  • 2-Pyrimidinamine, 4-iodo-
  • 4-Iodopyrimidin-2-amine ISO 9001：2015 REACH
  • 815610-16-3
  • Heterocycle-Pyrimidine series
  • pyrimidine