ChemicalBook > CAS DataBase List > 1H-Pyrazolo[3,4-b]pyridin-3(2H)-one

1H-Pyrazolo[3,4-b]pyridin-3(2H)-one

Product Name: 1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
CAS No.: 2942-43-0
Chemical Name: 1H-Pyrazolo[3,4-b]pyridin-3(2H)-one
Synonyms: 1h-pyrazolo[3,4-b]pyridin-3-ol;1H-Pyrazolo[3,4-b]pyridin-3(2H);1H,2H-pyrazolo[3,4-b]pyridin-3-one;1H-Pyrazolo[3,4-b]pyridin-3(2H)-one;3-Hydroxy-1H-pyrazolo[3,4-b]pyridine;1H,2H,3H-pyrazolo[3,4-b]pyridin-3-one;1,2-dihydropyrazolo[3,4-b]pyridin-3-one;1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one;3H-Pyrazolo[3,4-b]pyridin-3-one, 1,2-dihydro-
CBNumber: CB72471568
Molecular Formula: C6H5N3O
Formula Weight: 135.12
MOL File: 2942-43-0.mol

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1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Property

Melting point:: 234-236°
Density: 1.62±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 8.93±0.20(Predicted)
Appearance: Yellow to brown Solid

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 048684
Product name: 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Purity: >95%
Packaging: 500mg
Price: $220
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD142015
Product name: 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Packaging: 1g
Price: $350
Updated: 2021/12/16

Matrix Scientific

Product number: 048684
Product name: 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Purity: >95%
Packaging: 1g
Price: $370
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD142015
Product name: 1,2-Dihydro-3H-pyrazolo[3,4-b]pyridin-3-one
Packaging: 2g
Price: $595
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0080114
Product name: 1,2-DIHYDRO-3H-PYRAZOLO[3,4-B]PYRIDIN-3-ONE
Purity: 95.00%
Packaging: 1G
Price: $925.31
Updated: 2021/12/16

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1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Chemical Properties,Usage,Production

Synthesis

1452-94-4

2942-43-0

General procedure for the synthesis of 1H-pyrazolo[3,4-b]pyridin-3(2H)-one from ethyl 2-chloropyridine-3-carboxylate: a mixed solution of 5 g (26.94 mmol) of ethyl 2-chloropyridine-3-carboxylate and 4.76 g (80.82 mmol) of 85% hydrazine hydrate in 10 ml of ethanol was heated and refluxed for 6 hours. After completion of the reaction, the reaction mixture was concentrated. The product 3.5 g was obtained in 96% yield and the [M+H]+ peak was detected as 135.9 by mass spectrometry.

References

[1] Patent: WO2005/73199, 2005, A1. Location in patent: Page/Page column 31
[2] Patent: US2005/197348, 2005, A1. Location in patent: Page/Page column 10

1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Pyrazolo[3,4-b]pyridin-3(2H)-one Suppliers

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2942-43-0, 1H-Pyrazolo[3,4-b]pyridin-3(2H)-oneRelated Search:

1H-Pyrazolo[3,4-b]pyridin-3(2H)-one

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1h-pyrazolo[3,4-b]pyridin-3-ol

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1H-Pyrazolo[3,4-b]pyridin-3(2H)

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2942-43-0