ChemicalBook > CAS DataBase List > trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid

trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid

Product Name
trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid
CAS No.
892489-52-0
Chemical Name
trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid
Synonyms
AZD-3988;AZD-3988,AZD3988;AZD-3988; AZD3988; AZD 3988;2-[4-[4-[[5-(3,4-Difluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]cyclohexyl]acetic acid;2-(trans-4-(4-(5-((3,4-Difluorophenyl)amino)-1,3,4-oxadiazole-2-carboxamido)phenyl)cyclohexyl)acetic acid;trans-4-[-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid;trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid;Cyclohexaneacetic acid, 4-[4-[[[5-[(3,4-difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]-, trans-
CBNumber
CB72484986
Molecular Formula
C23H22F2N4O4
Formula Weight
456.44
MOL File
892489-52-0.mol
More
Less

trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid Property

Density 
1.402
storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in DMSO and to 10 mM in 1eq. NaOH with gentle warming
form 
Powder
pka
4.72±0.10(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
4837
Product name
AZD3988
Purity
≥98%(HPLC)
Packaging
10
Price
$368
Updated
2021/12/16
Tocris
Product number
4837
Product name
AZD3988
Purity
≥98%(HPLC)
Packaging
50
Price
$1449
Updated
2021/12/16
TRC
Product number
A808228
Product name
AZD3988
Packaging
2.5mg
Price
$440
Updated
2021/12/16
ChemScene
Product number
CS-0004334
Product name
AZD3988
Purity
98.62%
Packaging
5mg
Price
$450
Updated
2021/12/16
ApexBio Technology
Product number
B4944
Product name
AZD3988
Packaging
5mg
Price
$709
Updated
2021/12/16
More
Less

trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid Chemical Properties,Usage,Production

Uses

AZD 3988 is a diacylglycerol O-acyltransferase (DGAT) enzyme inhibitor, which has been investigated as potential treatments for diabetes and other metabolic diseases.

in vivo

AZD3988 (compound 53) shows (i.v., p.o.; 0.5, 1, 2, 5 mg/kg) has good pharmacokinetics in vivo efficacy[1].

Animal Model:Mouse, Rats and Dog[1]
Dosage:0.5, 1, 2, 5 mg/kg
Administration:IV at 0.5 mg/kg (mouse), 2 mg/kg (rat) and 1 mg/kg (dog) and po at 1 mg/kg (mouse), 5 mg/kg(rat) and 1 mg/kg (dog)
Result:
SpeciesClp (mL/min/kg)Vdss(L/kg) IV half-life (h) po half-life (h)po Cmax(lM)Bioavailability (%)
Mouse4.60.994.94.71.9>100
Rat1.10.353.45.820>100
Dog2.50.361.85.71.532

storage

Store at +4°C

trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid Suppliers

China 28 India 1 United Kingdom 1 United States 10 Global 40
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4769
Advantage
55
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 18438616290
Email
lanwu@univ-bio.com
Country
China
ProdList
24731
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7982
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
5929
Advantage
58
Hubei Chuchang Chemical Co., Ltd
Tel
18 15623560702
Email
info@chuchangbiotech.com
Country
China
ProdList
162
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
Advantage
58
Shanghai Fine Biotech Co.，Ltd
Tel
18221172427
Email
sale@fine-biotech.com
Country
China
ProdList
2760
Advantage
58
R&D Systems, Inc
Tel
18003437475
Fax
1-612-656-4400
Email
rdname@qq.com
Country
China
ProdList
6960
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
Hubei Chuchang Biotech Co., Ltd.
Tel
+undefined15623860702
Email
info@chuchangbiotech.com
Country
China
ProdList
202
Advantage
58
Guangzhou Yiran Biotechnology Co., Ltd.
Tel
15571990006
Country
CHINA
ProdList
141
Advantage
58
Guangzhou Weisheng Biotechnology Co., Ltd.
Tel
17765667235
Country
CHINA
ProdList
129
Advantage
58
Guangzhou Haotian Biotechnology Co., Ltd.
Tel
15571990006
Country
CHINA
ProdList
122
Advantage
58
Guangzhou Kati Biotechnology Co., Ltd.
Tel
13128698830
Country
CHINA
ProdList
199
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6525
Advantage
58
Shanghai Chaoyan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
471161314@qq.com
Country
CHINA
ProdList
6210
Advantage
58
Shanghai Haoyang Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
596799915@QQ.COM
Country
CHINA
ProdList
2905
Advantage
58
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58
More
Less

View Lastest Price from trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid manufacturers

Hubei Chuchang Biotech Co., Ltd.
Product
AZD-3988,AZD3988 892489-52-0
Price
US $0.00-0.00/mg
Min. Order
1mg
Purity
98
Supply Ability
20G
Release date
2024-10-29

892489-52-0, trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acidRelated Search:

DIFLUOROIODOMETHANE 2,6-Difluorobenzonitrile Difluoromethane

  • trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid
  • AZD-3988; AZD3988; AZD 3988
  • trans-4-[-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid
  • AZD-3988
  • Cyclohexaneacetic acid, 4-[4-[[[5-[(3,4-difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]-, trans-
  • 2-[4-[4-[[5-(3,4-Difluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]cyclohexyl]acetic acid
  • AZD-3988,AZD3988
  • 2-(trans-4-(4-(5-((3,4-Difluorophenyl)amino)-1,3,4-oxadiazole-2-carboxamido)phenyl)cyclohexyl)acetic acid
  • 892489-52-0
  • C23H22F2N4O4