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Methyl 5-bromo-7-azaindole-3-carboxylate

Product Name
Methyl 5-bromo-7-azaindole-3-carboxylate
CAS No.
872619-43-7
Chemical Name
Methyl 5-bromo-7-azaindole-3-carboxylate
Synonyms
Methyl 5-bromo-7-azaindole-3-carboxylate;Methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate;5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester;1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-, Methyl ester
CBNumber
CB72485620
Molecular Formula
C9H7BrN2O2
Formula Weight
255.07
MOL File
872619-43-7.mol
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Methyl 5-bromo-7-azaindole-3-carboxylate Property

Density 
1.709±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
11.33±0.40(Predicted)
Appearance
Off-white to light brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M296570
Product name
Methyl5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate
Packaging
50mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-B0568
Product name
1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,5-bromo-,methylester
Purity
96.95%
Packaging
250mg
Price
$117
Updated
2021/12/16
ChemScene
Product number
CS-B0568
Product name
1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,5-bromo-,methylester
Purity
96.95%
Packaging
100mg
Price
$90
Updated
2021/12/16
AK Scientific
Product number
3838AH
Product name
Methyl5-bromo-1H-pyrrolo[2,3-B]pyridine-3-carboxylate
Packaging
100mg
Price
$163
Updated
2021/12/16
ChemScene
Product number
CS-B0568
Product name
1H-Pyrrolo[2,3-b]pyridine-3-carboxylicacid,5-bromo-,methylester
Purity
96.95%
Packaging
1g
Price
$172
Updated
2021/12/16
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Methyl 5-bromo-7-azaindole-3-carboxylate Chemical Properties,Usage,Production

Uses

Methyl 5-bromo-7-azaindole-3-carboxylate is an organic synthesis intermediate, mainly used in the synthesis of biologically active compounds as a key building block in the synthesis process.

Synthesis

67-56-1

849068-61-7

872619-43-7

5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (480 mg, 2 mmol, 1.0 eq.) was used as a starting material and mixed with concentrated hydrochloric acid. A methanol solution containing sulfuric acid (0.5 mL, catalytic amount) was added to the mixture and the reaction mixture was subsequently refluxed for 24 hours. Upon completion of the reaction, the solvent was removed by concentration via rotary evaporator. The obtained residue was dissolved in ethyl acetate and subsequently washed with saturated aqueous sodium bicarbonate solution. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (450 mg, 85% yield) as a white solid.LCMS analysis showed (M+H)+ m/z calculated value of 256.1 and measured value of 256.1.

References

[1] Patent: WO2018/11628, 2018, A1. Location in patent: Paragraph 00694
[2] Patent: WO2016/178110, 2016, A1. Location in patent: Page/Page column 150
[3] Patent: WO2006/1754, 2006, A1. Location in patent: Page/Page column 21-22

Methyl 5-bromo-7-azaindole-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 5-bromo-7-azaindole-3-carboxylate Suppliers

China 58 India 1 United States 4 Global 63
Aladdin Scientific
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United States
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Synthonix Inc
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SynQuest Laboratories, Inc.
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Matrix Scientific
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sales@matrixscientific.com
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872619-43-7, Methyl 5-bromo-7-azaindole-3-carboxylateRelated Search:

1H-Imidazo[4,5-b]pyridine,5-bromo-(8CI) 5-BROMO-1H-PYRROLO[2,3-C]PYRIDIN-2(3H)-ONE 5-Bromo-4-azaindole 5-BroMo-4-azaindole-3-carbaldehyde 5-bromo-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one

  • Methyl 5-bromo-7-azaindole-3-carboxylate
  • 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-, Methyl ester
  • 5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester
  • Methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylate
  • 872619-43-7