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4-Hydroxy Cholesterol-d7

Product Name
4-Hydroxy Cholesterol-d7
CAS No.
1246302-80-6
Chemical Name
4-Hydroxy Cholesterol-d7
Synonyms
4-Hydroxy Cholesterol-d7;4β-Hydroxy Cholesterol-d7;cholest-5-ene-3,4-diol-d7;2H7]-4β-Hydroxycholesterol;4-beta-Hydroxy Cholesterol-d7;CHOLEST-5-ENE-3,4-DIOL-D7;4-HYDROXYCHOLESTEROL-D7;(3S,4R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6,7,7,7-tetradeuterio-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,4-diol
CBNumber
CB72487154
Molecular Formula
C27H46O2
Formula Weight
402.65294
MOL File
1246302-80-6.mol
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4-Hydroxy Cholesterol-d7 Property

Melting point:
154-159°C
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25971
Product name
4β-hydroxy Cholesterol-d7
Purity
≥99% deuterated forms (d1-d7)
Packaging
500μg
Price
$189
Updated
2024/03/01
Cayman Chemical
Product number
25971
Product name
4β-hydroxy Cholesterol-d7
Purity
≥99% deuterated forms (d1-d7)
Packaging
1mg
Price
$359
Updated
2024/03/01
TRC
Product number
H917982
Product name
4β-HydroxyCholesterol-d7
Packaging
1mg
Price
$205
Updated
2021/12/16
Usbiological
Product number
013561
Product name
4β-Hydroxy Cholesterol-d7
Packaging
1mg
Price
$496
Updated
2021/12/16
AK Scientific
Product number
0465CK
Product name
Cholest-5-en-3beta,4beta-diol(d7)
Packaging
1mg
Price
$498
Updated
2021/12/16
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4-Hydroxy Cholesterol-d7 Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.

Uses

4β-hydroxycholesterol-d7 has been used:

  • as an internal standard to spike plasma samples ultra-high-pressure liquid,chromatography–tandem mass spectrometry (UHPLC-MS/MS) analysis
  • to spike serum samples for mass spectrometry measurements
  • as an internal standard for the quantification of human colon biopsies samples using HPLC-MS

General Description

4β-hydroxycholesterol (4β-HC) is a catabolic product of cholesterol metabolism mediated by the enzyme cytochrome P450 family 3 subfamily A member 4 (CYP3A4). 4β-hydroxycholesterol-d7 is the deuterated form of 4β-hydroxycholesterol.

Biochem/physiol Actions

4β-hydroxycholesterol (4β-HC) may function as a liver X receptor ligand. The levels of 4β-HC are elevated in dextran sulfate induced colitis along with other oxysterols and it may promote colon inflammation.

4-Hydroxy Cholesterol-d7 Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy Cholesterol-d7 Suppliers

J & K SCIENTIFIC LTD.
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1246302-80-6, 4-Hydroxy Cholesterol-d7Related Search:


  • 4-Hydroxy Cholesterol-d7
  • CHOLEST-5-ENE-3,4-DIOL-D7;4-HYDROXYCHOLESTEROL-D7
  • (3S,4R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6,7,7,7-tetradeuterio-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,4-diol
  • 4-beta-Hydroxy Cholesterol-d7
  • cholest-5-ene-3,4-diol-d7
  • 4β-Hydroxy Cholesterol-d7
  • 2H7]-4β-Hydroxycholesterol
  • 1246302-80-6
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids
  • Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids