5-Methyl-3-nitro-2-pyridinecarbonitrile
- Product Name
- 5-Methyl-3-nitro-2-pyridinecarbonitrile
- CAS No.
- 1089330-68-6
- Chemical Name
- 5-Methyl-3-nitro-2-pyridinecarbonitrile
- Synonyms
- 5-Methyl-3-nitropicolinonitrile;2-Cyano-5-methyl-3-nitropyridine;5-Methyl-3-nitropyridin-2-carbonitrile;5-Methyl-3-nitro-2-pyridinecarbonitrile;5-Methyl-3-nitro-pyridine-2-carbonitrile;2-Pyridinecarbonitrile, 5-Methyl-3-nitro-;5-Methyl-3-nitro-2-pyridinecarbonitrile ISO 9001：2015 REACH
- CBNumber
- CB72500569
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 1089330-68-6.mol
5-Methyl-3-nitro-2-pyridinecarbonitrile Property
- Density
- 1.34
- storage temp.
- Inert atmosphere,Room Temperature
- form
- crystal
- color
- yellow
N-Bromosuccinimide Price
- Product number
- M220923
- Product name
- 5-Methyl-3-nitropicolinonitrile
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M220923
- Product name
- 5-Methyl-3-nitropicolinonitrile
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 1767AA
- Product name
- 5-Methyl-3-nitropicolinonitrile
- Packaging
- 100mg
- Price
- $154
- Updated
- 2021/12/16
- Product number
- 300731
- Product name
- 5-Methyl-3-nitro-2-pyridinecarbonitrile, 97%
- Packaging
- 1g
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 059156
- Product name
- 5-Methyl-3-nitro-pyridine-2-carbonitrile
- Purity
- 95+%
- Packaging
- 1g
- Price
- $435
- Updated
- 2021/12/16
5-Methyl-3-nitro-2-pyridinecarbonitrile Chemical Properties,Usage,Production
Synthesis
23056-46-4
544-92-3
1089330-68-6
2-Bromo-5-methyl-3-nitropyridine (60.53 g, 278.9 mmol) and cuprous cyanide (CuCN, 27.52 g, 307.3 mmol) were added to a round bottom flask. The flask was evacuated and displaced three times with nitrogen to remove air. N,N-dimethylformamide (DMF, 150 mL) was added slowly through a constant pressure dropping funnel. The reaction mixture was heated to 70 °C and kept stirring for 1.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently poured into a mixture of ethyl acetate (EtOAc, 500 mL) and water (250 mL). The mixture was filtered through a bed of diatomaceous earth (1 cm thickness) to remove insoluble impurities. The organic and aqueous phases were separated, and the organic phase was washed sequentially with deionized water (2 × 100 mL) and 1:1 saturated ammonium chloride/ammonia solution (2 × 100 mL). The aqueous phases were combined and back-extracted with ethyl acetate (2 × 200 mL). All organic phases were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to afford the target product 5-methyl-3-nitropyridine-2-carbonitrile (36.10 g, 79% yield).
References
[1] Patent: WO2009/9740, 2009, A1. Location in patent: Page/Page column 52
5-Methyl-3-nitro-2-pyridinecarbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Methyl-3-nitro-2-pyridinecarbonitrile manufacturers
- Product
- 5-Methyl-3-nitro-2-pyridinecarbonitrile 1089330-68-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-23