Benzyl 6-aminonicotinate
- Product Name
- Benzyl 6-aminonicotinate
- CAS No.
- 935687-49-3
- Chemical Name
- Benzyl 6-aminonicotinate
- Synonyms
- Benzyl 6-aminonicotinate;6-Aminonicotinic acid benzyl ester;Benzyl 6-aminopyridine-3-carboxylate;2-Amino-5-(benzyloxycarbonyl)pyridine;3-Pyridinecarboxylic acid, 6-amino-, phenylmethyl ester
- CBNumber
- CB72502482
- Molecular Formula
- C13H12N2O2
- Formula Weight
- 228.25
- MOL File
- 935687-49-3.mol
Benzyl 6-aminonicotinate Property
- Boiling point:
- 420.5±30.0 °C(Predicted)
- Density
- 1.243±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 4.71±0.13(Predicted)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B225075
- Product name
- Benzyl6-aminonicotinate
- Packaging
- 250mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CHM0391922
- Product name
- BENZYL-6-AMINONICOTINATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.96
- Updated
- 2021/12/16
- Product number
- CM177603
- Product name
- benzyl6-aminonicotinate
- Purity
- 98%
- Packaging
- 5g
- Price
- $533
- Updated
- 2021/12/16
- Product number
- CD11009698
- Product name
- Benzyl6-aminonicotinate
- Purity
- 98%
- Packaging
- 5g
- Price
- $564
- Updated
- 2021/12/16
- Product number
- 935687493
- Product name
- Benzyl6-aminonicotinate
- Packaging
- 5g
- Price
- $581.4
- Updated
- 2021/12/16
Benzyl 6-aminonicotinate Chemical Properties,Usage,Production
Synthesis
3167-49-5
100-39-0
935687-49-3
Example 46 Procedure for the synthesis of benzyl 6-{3-[7-fluoro-2-(4-fluorobenzyl)-3-oxo-2,3-dihydro-1H-isoindol-1-yl]-propionylamino}- nicotinate: A. Synthesis of benzyl 6-aminonicotinate: to a mixture of DMF (4 mL) containing 6-aminonicotinic acid (1.0 g, 7.2 mmol) and potassium carbonate (1.5 g, 10.8 mmol), benzyl bromide (0.86 ml, 7.9 mmol) was added. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the reaction mixture was diluted with water (50 mL) and extracted with ethyl acetate (3 x 50 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give the crude product. The crude product was recrystallized with ether to give the title compound as a light yellow solid (0.88 g, 53% yield).
References
[1] Patent: WO2010/29461, 2010, A1. Location in patent: Page/Page column 65-66
[2] Patent: US2007/99930, 2007, A1. Location in patent: Page/Page column 48
[3] Patent: US2011/190267, 2011, A1. Location in patent: Page/Page column 53
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 3, p. 1318 - 1333
Benzyl 6-aminonicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
Benzyl 6-aminonicotinate Suppliers
- Tel
- --
- Fax
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- sales@apolloscientific.co.uk
- Country
- United Kingdom
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