2-(4-BROMOPHENYL)THIOPHENE
- Product Name
- 2-(4-BROMOPHENYL)THIOPHENE
- CAS No.
- 40133-22-0
- Chemical Name
- 2-(4-BROMOPHENYL)THIOPHENE
- Synonyms
- 2-(4-BROMOPHENYL)THIOPHENE;2-(4-Bromophenyl)thiophene97%;1-Bromo-4-(thien-2-yl)benzene;Thiophene, 2-(4-bromophenyl)-;2-(4-Bromophenyl)thiophene 97%
- CBNumber
- CB7250532
- Molecular Formula
- C10H7BrS
- Formula Weight
- 239.13
- MOL File
- 40133-22-0.mol
2-(4-BROMOPHENYL)THIOPHENE Property
- Melting point:
- 95-99 °C (lit.)
- Boiling point:
- 307.0±17.0 °C(Predicted)
- Density
- 1.490±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- powder to crystal
- color
- White to Light yellow
Safety
- RIDADR
- UN 3335
- WGK Germany
- 3
- Hazard Note
- Harmful
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 596663
- Product name
- 2-(4-Bromophenyl)thiophene
- Purity
- 97%
- Packaging
- 1g
- Price
- $70
- Updated
- 2023/01/07
- Product number
- B5106
- Product name
- 2-(4-Bromophenyl)thiophene
- Purity
- >97.0%(GC)
- Packaging
- 1g
- Price
- $154
- Updated
- 2025/07/31
- Product number
- B5106
- Product name
- 2-(4-Bromophenyl)thiophene
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $615
- Updated
- 2025/07/31
- Product number
- B687735
- Product name
- 2-(4-Bromophenyl)thiophene
- Packaging
- 1g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- W9929
- Product name
- 2-(4-Bromophenyl)thiophene
- Packaging
- 1g
- Price
- $151
- Updated
- 2021/12/16
2-(4-BROMOPHENYL)THIOPHENE Chemical Properties,Usage,Production
Uses
2-(4-Bromophenyl)thiophene is a reagent in the synthesis of 6-O-arylpropargyl diazalides, which has activity against Streptococcus pneumoniae.
Synthesis
589-87-7
193978-23-3
40133-22-0
General procedure for the synthesis of 2-(4-bromophenyl)thiophene from p-bromoiodobenzene and 2-thiophene boronic acid pinacol ester: 1-bromo-4-iodobenzene (2.0 g, 7.07 mmol), 4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane (2.97 g, 14.1 mmol), Pd(PPh3)4 ( 408 mg, 0.35 mmol) and Na2CO3 (1.49 g, 14.1 mmol) were dissolved in a solvent mixture of toluene (40 mL), THF (15 mL) and H2O (15 mL). The reaction mixture was heated to reflux. Upon completion of the reaction (monitored by TLC), the solvent was removed by distillation under reduced pressure, extracted by addition of H2O (30 mL) and CH2Cl2 (40 mL), the organic layer was separated and dried over anhydrous MgSO4. The crude product was purified by silica gel fast column chromatography to afford 2-(4-bromophenyl)thiophene (1.26 g, 74.6% yield). The spectral data of the obtained product were consistent with the values reported in the literature.1H NMR (400 MHz, CDCl3): δ 7.48 (d, J = 3.6 Hz, 4H), 7.29 (d, J = 4.4 Hz, 2H), 7.07 (dt, J = 1.4, 4.4 Hz, 1H).
References
[1] Journal of Nanoscience and Nanotechnology, 2016, vol. 16, # 1, p. 910 - 919
[2] ChemPlusChem, 2017, vol. 82, # 5, p. 742 - 749
2-(4-BROMOPHENYL)THIOPHENE Preparation Products And Raw materials
Raw materials
Preparation Products
2-(4-BROMOPHENYL)THIOPHENE Suppliers
- Tel
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- Country
- Belgium
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- 6293
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View Lastest Price from 2-(4-BROMOPHENYL)THIOPHENE manufacturers
- Product
- 2-(4-BROMOPHENYL)THIOPHENE 40133-22-0
- Price
- US $1.00-100.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 300KG
- Release date
- 2024-08-19