6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt
- Product Name
- 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt
- CAS No.
- 479347-86-9
- Chemical Name
- 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt
- Synonyms
- NSC7169;NSC 7169;NSC-7169;NBQX sodium;3-dione . 2Na;NBQX (sodium salt);FG 9202 disodium salt;6-Nitro-7-sulphamoylbenzo(f)-quinoxaline-2;NBQX disodium salt, AMPA / kainate antagonist;6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE-2;3-DIONE . 2NA;FG 9202 DISODIUM SALT
- CBNumber
- CB72511387
- Molecular Formula
- C24H14N8Na2O12S2
- Formula Weight
- 716.5239
- MOL File
- 479347-86-9.mol
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Property
- storage temp.
- -20°C Freezer
- solubility
- Soluble in H2O
- form
- crystalline solid
- color
- Orange
- Water Solubility
- Soluble to 100 mM in water
- Stability:
- Store in Freezer at -20°C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 14914
- Product name
- NBQX (sodium salt)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $111
- Updated
- 2024/03/01
- Product number
- 14914
- Product name
- NBQX(sodiumsalt)
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $874
- Updated
- 2024/03/01
- Product number
- 14914
- Product name
- NBQX (sodium salt)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 14914
- Product name
- NBQX (sodium salt)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $262
- Updated
- 2024/03/01
- Product number
- 14914
- Product name
- NBQX (sodium salt)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $493
- Updated
- 2024/03/01
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Chemical Properties,Usage,Production
Chemical Properties
Deep Red-Brown Solid
Uses
A potent and discriminating antagonist for AMPA binding sites.
Biological Activity
nbqx disodium salt is a potent, highly selective and competitive antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (ampa) receptors (ampars). the ampar is one type of ionotropic glutamate receptors, well known to be involved in various neurological disorders such as alzheimer disease, schizophrenia, and epilepsy, by mediating long-term potentiation, excitotoxicity, or both. inhibition of ampars with nbqx shows neuroprotective and anticonvulsant activity.1. fukushima k, tabata y, imaizumi y, et al. characterization of human hippocampal neural stem/progenitor cells and their application to physiologically relevant assays for multiple ionotropic glutamate receptors. journal of biomolecular screening, 2014, 19(8): 1174-1184.2. chen w, li ys, gao j, et al. ampa receptor antagonist nbqx decreased seizures by normalization of perineuronal nets. plos one, 2016, 11(11): e0166672.
storage
-20°C
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Preparation Products And Raw materials
Raw materials
Preparation Products
6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt Suppliers
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