Desmosterol-d6
- Product Name
- Desmosterol-d6
- CAS No.
- 1246298-67-8
- Chemical Name
- Desmosterol-d6
- Synonyms
- Desmosterol-d6;[2H6]-Desmosterol;24-dehydro Cholesterol-d6;cholesta-5,24-dien-3-ol-d6;cholesta-5,24-dien-3β-ol-d6;Desmosterol-26,26,26,27,27,27-d6;CHOLESTA-5,24-DIEN-3-OL-D6;DESMOSTEROL-D6
- CBNumber
- CB72512379
- Molecular Formula
- C27H44O
- Formula Weight
- 384.63766
- MOL File
- 1246298-67-8.mol
Desmosterol-d6 Property
- Melting point:
- 114-116°C
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- color
- Off-White to Light Beige
N-Bromosuccinimide Price
- Product number
- 26777
- Product name
- 24-dehydro Cholesterol-d6
- Packaging
- 500μg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 26777
- Product name
- 24-dehydro Cholesterol-d6
- Packaging
- 1mg
- Price
- $230
- Updated
- 2024/03/01
- Product number
- D296862
- Product name
- Desmosterol-d6
- Packaging
- 1mg
- Price
- $245
- Updated
- 2021/12/16
Desmosterol-d6 Chemical Properties,Usage,Production
Description
24-dehydro Cholesterol-d6 is intended for use as an internal standard for the quantification of 24-dehydro cholesterol by GC- or LC-MS. 24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.
Uses
A labelled metabolite of Cholesterol (C432501).
Desmosterol-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
Desmosterol-d6 Suppliers
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