5-Bromo-7-methyl-1H-indole
- Product Name
- 5-Bromo-7-methyl-1H-indole
- CAS No.
- 15936-81-9
- Chemical Name
- 5-Bromo-7-methyl-1H-indole
- Synonyms
- EOS-61850;5-BroMo-7-Methylindole;7-methyl-5-bromo-1H-indole;5-Bromo-7-methyl-1H-indole;1H-Indole, 5-bromo-7-methyl-
- CBNumber
- CB72516322
- Molecular Formula
- C9H8BrN
- Formula Weight
- 210.07
- MOL File
- 15936-81-9.mol
5-Bromo-7-methyl-1H-indole Property
- Boiling point:
- 165 °C(Press: 0.1 Torr)
- Density
- 1.503 g/mL at 25 °C
- refractive index
- n20/D1.648
- Flash point:
- >110℃
- storage temp.
- Sealed in dry,Room Temperature
- form
- Solid or semi-solid or lump or liquid
- pka
- 16.34±0.30(Predicted)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B814625
- Product name
- 5-Bromo-7-methyl-1H-indole
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- HCH0066687
- Product name
- 5-BROMO-7-METHYLINDOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $712.86
- Updated
- 2021/12/16
- Product number
- 8015AA
- Product name
- 5-Bromo-7-methyl-1H-indole
- Packaging
- 100mg
- Price
- $111
- Updated
- 2021/12/16
- Product number
- 132930
- Product name
- 5-Bromo-7-methyl-Indole
- Purity
- 95%
- Packaging
- 5g
- Price
- $1764
- Updated
- 2021/12/16
- Product number
- 132930
- Product name
- 5-Bromo-7-methyl-Indole
- Purity
- 95%
- Packaging
- 10g
- Price
- $2700
- Updated
- 2021/12/16
5-Bromo-7-methyl-1H-indole Chemical Properties,Usage,Production
Synthesis
5-Bromo-7-methyl-1H-indole is synthesised from 4-bromo-6-(trimethylsilylacetylenyl)-2-methylaniline by reacting with potassium tert-butyrate and sodium hydride in the presence of inert gas. The steps are as follows:
Add sodium hydride (2.64g, 0.11mol) and DMF (70mL) to a 250ml three-necked flask at room temperature and under nitrogen protection.Stir and dissolve; a solution of the compound of formula IV (14g, 0.05mol) dissolved in DMF (30mL) is slowly added dropwise to the potassium tert-butoxide solution. After the addition, the reaction system was heated to 60 degrees and kept for 2 hours. After the reaction was completed, the reaction solution was poured into ice water, extracted with methyl tert-butyl ether, and washed with sodium bicarbonate aqueous solution and brine in turn.It was then dried over anhydrous sodium sulfate, filtered, and concentrated. The crude product is purified by silica gel column chromatography to obtain the compound of 5-bromo-7-methylindole. Yield: 8.36 g, yield: 80%.
5-Bromo-7-methyl-1H-indole Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-7-methyl-1H-indole Suppliers
View Lastest Price from 5-Bromo-7-methyl-1H-indole manufacturers
- Product
- 5-Bromo-7-methyl-1H-indole 15936-81-9
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-09