tert-butyl methyl(2-(methylamino)ethyl)carbamate
- Product Name
- tert-butyl methyl(2-(methylamino)ethyl)carbamate
- CAS No.
- 112257-19-9
- Chemical Name
- tert-butyl methyl(2-(methylamino)ethyl)carbamate
- Synonyms
- N1-Boc-N1,N2-dimethyl-1,2-ethanediamine;tert-butyl N-Methyl-N-[2-(MethylaMino)ethyl]carbaMate;N-Boc-N,N'-dimethylethylamine;tert-Butyl methyl(2-(methylamino);N-Boc-N,N'-dimethylethylamine 95%;(N-BOC-N,N-DIMETHYL)ETHYLENEDIAMINE;tert-butyl methyl(2-(methylamino)ethyl)carbamate;N-Methyl-N'-Methyl-N'-t-butoxycarbonylethylenediaMine;N-[(tert-Butoxy)carbonyl]-N,N'-dimethylethylenediamine;[2-[(tert-Butoxycarbonyl)(methyl)amino]ethyl]methylamine
- CBNumber
- CB72518225
- Molecular Formula
- C9H20N2O2
- Formula Weight
- 188.27
- MOL File
- 112257-19-9.mol
tert-butyl methyl(2-(methylamino)ethyl)carbamate Property
- Boiling point:
- 244.5±19.0 °C(Predicted)
- Density
- 0.957±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 9.96±0.10(Predicted)
- form
- liquid
- color
- Colourless to light yellow
Safety
- HS Code
- 2921199990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D6253
- Product name
- tert-Butyl Methyl[2-(methylamino)ethyl]carbamate
- Purity
- min. 95.0 %
- Packaging
- 5G
- Price
- $155
- Updated
- 2025/07/31
- Product number
- D6253
- Product name
- tert-Butyl Methyl[2-(methylamino)ethyl]carbamate
- Purity
- min. 95.0 %
- Packaging
- 25G
- Price
- $465
- Updated
- 2025/07/31
- Product number
- B810070
- Product name
- tert-ButylMethyl(2-(methylamino)ethyl)carbamate
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B810070
- Product name
- tert-ButylMethyl(2-(methylamino)ethyl)carbamate
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB143658
- Product name
- tert-Butyl methyl(2-(methylamino)ethyl)carbamate
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
tert-butyl methyl(2-(methylamino)ethyl)carbamate Chemical Properties,Usage,Production
Synthesis
24424-99-5
110-70-3
112257-19-9
GENERAL STEPS: N,N'-dimethylethylenediamine (5.00 g, 57 mmol) was dissolved in dichloromethane (25 mL) and the solution was cooled to 0 °C. In another vessel, di-tert-butyl dicarbonate (5.00 g, 22 mmol) was dissolved in dichloromethane (25 mL), and the solution was subsequently added dropwise slowly to the reaction flask, maintaining the temperature at 0°C. After the dropwise addition, the reaction mixture was gradually warmed to room temperature and stirring was continued overnight. Upon completion of the reaction, the reaction was quenched with deionized water (20 mL) and extracted with dichloromethane (40 mL x 2). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated. The crude product obtained was purified by silica gel column chromatography using methanol/dichloromethane (1/20, V/V) as eluent to finally obtain the target compound tert-butyl methyl (2-(methylamino)ethyl)carbamate (4.37 g, 81%) as a colorless oil. Its structure was confirmed by 1H NMR (400 MHz, CDCl3) and HRMS (ESI): 1H NMR δ 3.39-3.36 (m, 2H, CH2), 2.95-2.90 (s, 3H, CH3), 2.76 (m, 2H, CH2), 2.48 (s, 3H, CH3), 1.48 (s, 9H, (CH3)3); HRMS (ESI) m/z [M + H]+ Calculated value: C9H21N2O2+ 189.1603, measured value: 189.1601.
References
[1] Journal of Medicinal Chemistry, 1992, vol. 35, # 3, p. 559 - 567
[2] Organic Letters, 2008, vol. 10, # 8, p. 1517 - 1520
[3] Organic and Biomolecular Chemistry, 2010, vol. 8, # 8, p. 1777 - 1780
[4] Journal of the American Chemical Society, 2014, vol. 136, # 9, p. 3695 - 3704
[5] Journal of Medicinal Chemistry, 1990, vol. 33, # 1, p. 97 - 101
tert-butyl methyl(2-(methylamino)ethyl)carbamate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from tert-butyl methyl(2-(methylamino)ethyl)carbamate manufacturers
- Product
- tert-butyl methyl(2-(methylamino)ethyl)carbamate 112257-19-9
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-12